Comparing two methods for lens implantation in cataract surgery for patients with pseudoexfoliation syndrome

Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome: Lens in the Bag-technique Versus Lens in the Ciliary Sulcus With Optic Capture Technique

Not applicable Interventional Medical University of Vienna · NCT06053554

This study is testing two different ways to implant lenses during cataract surgery to see which method works better for people with pseudoexfoliation syndrome.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment120 (estimated)
Ages60 Years to 100 Years
SexAll
SponsorMedical University of Vienna Academic / other
Locations1 site (Vienna)
Trial IDNCT06053554 on ClinicalTrials.gov

What this trial studies

This study aims to compare the surgical outcomes of two intraocular lens (IOL) implantation techniques in patients with cataracts and pseudoexfoliation syndrome. It is a prospective, intraindividual comparative study where each patient undergoes bilateral cataract surgery, with one eye receiving a 3-point IOL in the capsular bag and the other receiving a 3-point IOL haptics in the ciliary sulcus. The study will evaluate differences in lens tilt, decentration, and the frequency of capsular phimosis between the two methods. Highly experienced surgeons will perform the procedures using femtolaser technology to ensure precision.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 60 to 100 who require bilateral cataract surgery and have been diagnosed with pseudoexfoliation syndrome.

Not a fit: Patients with end-stage glaucoma, crystalline lens subluxation, or active inflammatory diseases of the eye may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and visual acuity for patients undergoing cataract surgery with pseudoexfoliation syndrome.

How similar studies have performed: While similar surgical techniques have been explored, this specific comparative approach in the context of pseudoexfoliation syndrome is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 60 - 100
* Necessity for bilateral cataract surgery with pseudoexfoliation syndrome
* willing to give informed consent and follow-up the duration of study

Exclusion Criteria:

* Endstage glaucoma
* Christalline lens sub/ luxation
* active inflammatory diseases of the eye

Where this trial is running

Vienna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Age Related CataractsPseudoexfoliation SyndromeFemtolaserSulcus-IOLAnterior segmentLens tilt and decentrationCapsular phimoses
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.