Comparing two methods for knee pain relief in osteoarthritis patients
Comparative Study Between Knee Genicular Nerve Ablation by Thermal Radiofrequency vs Thermal Radiofrequency Plus Alcohol Neurolysis for Treatment of Symptomatic Knee Osteoarthritis
This study is testing two different ways to relieve knee pain in people with osteoarthritis who can't have knee replacement surgery to see which one works better and lasts longer.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 52 (estimated) |
| Ages | 60 Years to 70 Years |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05980338 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness and duration of pain relief in patients with knee osteoarthritis by comparing two treatment methods: conventional thermal radiofrequency ablation of the genicular nerves alone versus the same method combined with alcohol neurolysis. Participants will be assessed for satisfaction and pain relief duration following the interventions. The study focuses on patients who are not candidates for knee replacement surgery and have confirmed osteoarthritis through x-ray imaging.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 60-70 years with knee osteoarthritis who are not suitable for knee replacement surgery.
Not a fit: Patients with neurological disorders, coagulopathy, infections at the injection site, or those under 60 or over 70 years old may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective pain management option for patients suffering from knee osteoarthritis.
How similar studies have performed: Other studies have shown promising results with thermal radiofrequency ablation for knee pain, but the combination with alcohol neurolysis is less commonly tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Both genders. 2. Age between 60-70 years. 3. ASA 1,2 \& 3 physical status. 4. x ray imaging confirming the osteoarthritis and unwell or not candidate for knee replacement surgery Exclusion Criteria: 1. Neurological disorders.(previous cerebrovascular stroke , neuropathy , or weakness ) 2. coagulopathy ( plt \< 50000, INR \> 1.7 ) 3. Infection at or near the injection site. 4. presence of pacemaker or defibrillator 5 - Acute knee injury. 6- age \< 60 or \>70 years
Where this trial is running
Cairo
- Ain Shams University Hospital — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Lydia E Zakhary, MD
- Email: lydia_zakhary@med.asu.edu.eg
- Phone: 00201222555128
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.