Comparing two methods for knee pain relief in osteoarthritis
Comparison of the Efficacy of Ultrasound-Guided Phenol Block and Corticosteroid-Local Anesthetic Block Applied to the Genicular Nerve in Patients With Knee Osteoarthritis
NA · Gaziler Physical Medicine and Rehabilitation Education and Research Hospital · NCT06265675
This study is testing which of two pain relief methods works better for people with knee pain from osteoarthritis who haven't found relief from other treatments.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 88 (estimated) |
| Ages | 50 Years to 80 Years |
| Sex | All |
| Sponsor | Gaziler Physical Medicine and Rehabilitation Education and Research Hospital (other) |
| Locations | 1 site (Ankara, Çankaya) |
| Trial ID | NCT06265675 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the efficacy of two neurolysis techniques, phenol block and corticosteroid-local anesthetic block, for treating knee pain in patients with osteoarthritis. Participants must have experienced knee pain for at least six months and have not responded to conservative treatments. The study will evaluate the effectiveness of these interventions in reducing pain levels, as measured by the Numeric Rating Scale (NRS). By assessing the outcomes of these two methods, the research seeks to identify the more effective approach for managing knee osteoarthritis pain.
Who should consider this trial
Good fit: Ideal candidates are patients with knee osteoarthritis experiencing significant pain who have not found relief from other treatments.
Not a fit: Patients with acute knee injuries, recent surgeries, or certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective pain management option for patients suffering from knee osteoarthritis.
How similar studies have performed: While there have been studies on neurolysis techniques, the specific comparison of phenol block versus corticosteroid-local anesthetic block in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with knee osteoarthritis must have pain at least 6 months * NRS score of knee pain equal or more than 5 * At least grade 3 in Kellgren-Lawrence grading scale * Non responsive to life style change, weight control, exercises program, medical treatment and the other conservative treatments (physical therapy, intraarticular injections) * Decreasing at NRS score more than %50 after diagnostic block * Those who accept the consent form Exclusion Criteria: * Patients who have acute knee injury * Surgery history in knee * Connective tissue disease that affect knee * Sciatica * Injection story in last 3 months * Psychiatric or neurologic diseases that affect study * Septic arthritis, active local or systemic infection * Coagulopathy * Pregnancy * Allergic reaction
Where this trial is running
Ankara, Çankaya
- Gaziler — Ankara, Çankaya, Turkey (RECRUITING)
Study contacts
- Study coordinator: Rabia Layık
- Email: rabialyk@gmail.com
- Phone: +905314087679
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Knee Osteoarthritis, Genicular nerve, Phenol, Neurolysis, Nerve Blockage