Comparing two methods for knee ligament reconstruction
Comparison of Two Graft Choices in Mediale Patellofemoral Ligament Reconstruction (MPFL) - A Randomized Controlled Trial.
NA · Aarhus University Hospital · NCT05706363
This study is testing two different surgical methods for fixing a knee ligament to see which one helps young people with chronic patellar dislocation feel more stable and have less pain after surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 15 Years to 40 Years |
| Sex | All |
| Sponsor | Aarhus University Hospital (other) |
| Locations | 1 site (Aarhus N) |
| Trial ID | NCT05706363 on ClinicalTrials.gov |
What this trial studies
This study aims to compare two surgical techniques for reconstructing the medial patellofemoral ligament (MPFL) to treat chronic patellar dislocation. One technique uses a gracilis graft with screw fixation, while the other employs quadriceps tendon grafts with anchor fixation. The study will evaluate which method offers better stability, less postoperative pain, and a lower rate of patellar reluxation. Patients aged 15 to 40 with a history of lateral patellar dislocation will be included in the trial.
Who should consider this trial
Good fit: Ideal candidates are patients aged 15 to 40 with a history of chronic lateral patellar dislocation.
Not a fit: Patients with rheumatoid arthritis, significant osteoarthritis, or previous knee ligament surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced pain for patients with chronic patellar dislocation.
How similar studies have performed: While similar surgical techniques have been explored, this specific comparison of graft choices in MPFL reconstruction is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients between 15 and 40 years of age with chronic tendency to lateral patellar dislocation (defined as 2 or more verified dislocation cases) * The growth zones must be found closed - verified by MRI scan Exclusion Criteria: * Patients with known rheumatoid arthritis. * Patients with arthroscopically detected osteoarthritis (grade 3 cartilage lesion) * Inability to follow a normal rehabilitation regime. * Previous ligament surgery in injured knees.
Where this trial is running
Aarhus N
- Division of Sports Trauma, Palle Juul-Jensens Boulevard 99 — Aarhus N, Denmark (RECRUITING)
Study contacts
- Study coordinator: Martin Lind, Professor
- Email: martinlind@dadlnet.dk
- Phone: +45 30248244
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Patellar Dislocation