Comparing two methods for draining fluid from the lungs in emergency departments

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The SPEEDTAP-trial is a multicenter clinical trial that investigates two different methods for performing thoracentesis in emergency departments. Patients will be randomly assigned to receive either manual fluid removal in the emergency department or passive fluid drainage using gravity in the radiology department. The primary goal is to determine which method allows for quicker drainage of pleural effusions, with secondary outcomes including length of hospital stay and safety measures. A total of 188 patients will be included in this study across four emergency departments in Central Denmark.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients ≥ 18 years admitted to the ED
* Pleural effusion detected by any imaging modality (e.g., bedside ultrasound, chest x-ray, computed tomography)
* Clinically justified need for thoracentesis ( symptomatic relief and/or define the etiology of the effusion
* Without contraindication for thoracentesis in the emergency department (e.g., anticoagulant treatment)

Exclusion Criteria:

* Life-threatening respiratory distress
* Not able to give consent
* Previous pleurodesis
* Effusion does not appear free-flowing due to septations or loculations / suspected empyema
* Prior enrollment in the trial
* If randomization is not possible because decision to insert a pigtail catheter is made in the radiology department

Where it's running

• Horsens Regional Hospital
  Horsens, Central Jutland, Denmark Recruiting
• Randers Regional Hospital
  Randers, Central Jutland, Denmark Recruiting
• Aalborg University Hospital
  Aalborg, North Denmark, Denmark Recruiting
• Esbjerg sygehus
  Esbjerg, South Region Denmark, Denmark Recruiting
• Aarhus University Hospital
  Aarhus, Central Jutland, Denmark Not yet recruiting
• Gødstrup Regional Hospital
  Gødstrup, Central Jutland, Denmark Not yet recruiting

Study contacts

• Principal investigator: Sandra T Langsted — Aarhus University Hospital
• Study coordinator: Sandra T Langsted
• Email: sandra.langsted@clin.au.dk
• Phone: +45 20 27 65 12

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.