Comparing two methods for coronary angiography access

Effectiveness of the Anatomical Snuff Box Approach for Coronary Angiography: Comparative Non-inferiority Study With the Radial Arterial Approach to the Wrist

NA · GCS Ramsay Santé pour l'Enseignement et la Recherche · NCT05725616

This study is testing if a new way to access the heart for angiography through the wrist's anatomical snuff box is as safe and effective as the traditional method for patients needing this procedure.

Quick facts

PhaseNA
Study typeInterventional
Enrollment326 (estimated)
Ages18 Years and up
SexAll
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche (other)
Locations1 site (Villeurbanne)
Trial IDNCT05725616 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of the anatomical snuff box approach for coronary angiography compared to the traditional radial approach at the wrist. It focuses on patients scheduled for diagnostic coronary angiography and assesses whether the distal radial arterial approach is not inferior in terms of safety and efficacy. The study will involve patients aged 18 and over who have a detectable radial pulse at both the snuff box and wrist. By comparing these two methods, the research seeks to identify potential advantages of the distal approach in reducing complications.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older scheduled for diagnostic coronary angiography via the radial route.

Not a fit: Patients requiring emergency coronary angiography or those with severe contraindications will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a safer and more effective method for performing coronary angiography.

How similar studies have performed: While the radial approach is well-established, few studies have directly compared the distal radial approach to the traditional method, making this research relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient, male or female, aged 18 and over
* Patient having a diagnostic coronary angiography programmed by radial route.
* Patient with a radial pulse at the anatomical snuff box and at the wrist noticeable

Exclusion Criteria:

* Patient requiring emergency coronary angiography or having an acute coronary syndrome
* Patient with severe arteriopathy of the supra-aortic trunks
* Patient with a history of coronary bypass surgery
* Tall patients (\>1.90m)
* Patient allergic to xylocaine
* Patient presenting a contraindication to the realization of a coronary angiography:

terminal IRC, pregnancy, severe sepsis....

Where this trial is running

Villeurbanne

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Coronary Angiography

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.