Comparing two laser wavelengths for treating varicose veins

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of two different wavelengths (1940 nm and 1470 nm) used in Endovenous Laser Ablation (EVLA) for treating varicose veins in the lower limbs. The study will assess whether the higher wavelength improves treatment efficacy and reduces complications or pain compared to the lower wavelength. Participants will undergo laser ablation and will be monitored for five years to evaluate clinical outcomes, potential complications, and quality of life. The trial will involve patients with primary insufficiency of the great or small saphenous veins who meet specific inclusion criteria.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Primary insufficiency of the great saphenous vein (GSV) and/or small saphenous vein (SSV)
* Patient candidate for endothermic treatment of the lower limbs
* CEAP: C2 - C6
* Patient with a target vein diameter (GSV and/or SSV) \>= 3 mm throughout the target vein segment
* Patient affiliated or beneficiary of a social security scheme
* Patient having signed the informed consent

Exclusion Criteria:

* Patient with a current serious pathology and/or a life expectancy of less than 5 years
* Patient who has had a deep or superficial vein thrombosis in the previous 6 months
* Obliterating arteriopathy of the lower limb concerned, with an IPS \< 0.8 or \> 1.3
* Patient with post-thrombotic obstructive syndrome at the popliteal and/or femoral and/or iliac stage on the ipsilateral lower limb
* Patient with primary or post-thrombotic axial deep venous reflux on the ipsilateral lower limb
* Suspicion of non-post-thrombotic iliac compression on echo-doppler
* Contraindication to the planned treatment technique
* Patient whose geographical distance is not compatible with the follow-up of the study
* Pregnant or breastfeeding women
* Patient linguistically or psychologically unable to understand the information given, to give informed consent or to answer the study questionnaires.
* Protected patients: Adults under guardianship, or other legal protection; Hospitalized without consent.

Where it's running

• Clinique Pasteur
  Toulouse, France Recruiting

Study contacts

• Principal investigator: Nicolas NEAUME, MD — Clinique Pasteur
• Study coordinator: Nicolas NEAUME, MD
• Email: nneaume@clinique-pasteur.com
• Phone: +33 5 61 16 13 03

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.