Comparing two laser techniques for bladder tumor removal
Thulium Fiber Laser (TFL) Versus MOSES Holmium Laser in the En-bloc Resection of Bladder Tumors: A Randomized Controlled Clinical Study
This study is testing two different laser methods for removing bladder tumors to see if one works better than the other for patients.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Thunder Bay Regional Health Research Institute Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Thunder Bay, Ontario) |
| Trial ID | NCT06373419 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the pathological and clinical outcomes of two laser techniques, MOSES Holmium and Thulium Fiber Laser (TFL), used in the transurethral enucleation of bladder tumors. Participants will be randomly assigned to receive either TFL or MOSES laser treatment during their bladder resection procedure. The study seeks to determine if one method offers superior results in terms of tumor removal and subsequent patient outcomes. By utilizing laser technology, the trial hopes to improve the accuracy of pathology analysis and reduce complications associated with traditional tumor resection methods.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with visual indications of bladder tumors identified through outpatient cystoscopy.
Not a fit: Patients with tumors that are not suitable for laser resection, such as muscle-invasive or metastatic tumors, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment outcomes and reduced complications for patients undergoing bladder tumor removal.
How similar studies have performed: While the use of laser techniques in bladder tumor removal is established, this specific comparison of MOSES and TFL lasers is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Over 18 years of age at the time of enrollment. 2. Patients presented with visual criteria suggesting bladder tumor by outpatient cystoscopy will be legible for inclusion. Exclusion Criteria: 1. Tumors deemed not eligible for laser resection as determined by the Urologist e.g. obvious muscle-invasive or metastatic at presentation 2. Synchronous either urethral tumors or upper urinary tract tumor 3. History of Carcinoma in situ 4. Contracted bladder
Where this trial is running
Thunder Bay, Ontario
- Thunder Bay Regional Health Sciences Centre — Thunder Bay, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Ahmed Z Ahmed — Thunder Bay Regional Health Sciences Centre
- Study coordinator: Rabail Siddiqui
- Email: rabail.siddiqui@tbh.net
- Phone: (807) 684-6000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.