Comparing two laparoscopic techniques for rectosigmoid resection

Conventional Laparoscopic-assisted Rectosigmoid Resection Versus Laparoscopic Rectosigmoid Resection With Intracorporeal Anastomosis and Transrectal Specimen Retrieval

PHASE2 · Universitaire Ziekenhuizen KU Leuven · NCT01033838

This study is testing two different surgical methods for removing part of the colon to see which one helps patients recover better after surgery.

Quick facts

PhasePHASE2
Study typeInterventional
Enrollment1 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorUniversitaire Ziekenhuizen KU Leuven (other)
Locations1 site (Leuven)
Trial IDNCT01033838 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to compare two surgical techniques for rectosigmoid resection: laparoscopic-assisted rectosigmoid resection and laparoscopic rectosigmoid resection with transrectal specimen retrieval. The study involves a hybrid approach where dissection is performed laparoscopically, and the specimen is retrieved through the rectum using an endobag. Patients will be included in a standardized perioperative care program called Enhanced Recovery After Surgery (ERAS) to optimize recovery. The trial will assess the effectiveness and outcomes of these two techniques over a short-term follow-up period.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18-90 with symptomatic recurrent diverticular disease, benign adenomatous polyps requiring surgery, or early non-transmural sigmoid tumors.

Not a fit: Patients who are unsuitable for laparoscopy, pregnant, or have significant comorbidities may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery for patients undergoing rectosigmoid resection.

How similar studies have performed: There are currently no available trials in the literature comparing these two specific techniques, making this approach novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-90
* Symptomatic recurrent diverticular disease
* Benign adenomatous polyp, requiring surgery
* Early non-transmural sigmoidtumor
* Signed written informed consent, approved by ethical committee

Exclusion Criteria:

* Patients unsuitable for laparoscopy
* Pregnancy
* ASA \>III
* Coagulation disorders
* Anti-coagulants

Where this trial is running

Leuven

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Symptomatic Recurrent Diverticular Disease, Benign Adenomatous Sigmoidal Polyp, Requiring Surgery, Early Non-transmural Sigmoidtumor

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.