Comparing two laparoscopic liver surgery techniques for liver cancer
A RCT Study of Laparoscopic Middle Hepatic Vein Guidance and Traditional Anatomic Hemihepatectomy
This study is testing two different laparoscopic surgery techniques for liver cancer to see which one helps patients recover better and have better outcomes.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 95 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Southwest Hospital, China Academic / other |
| Locations | 1 site (Chongqing, Chongqing) |
| Trial ID | NCT04422249 on ClinicalTrials.gov |
What this trial studies
This study aims to compare the effectiveness of laparoscopic middle hepatic vein guidance versus traditional anatomic hemihepatectomy in patients with hepatocellular carcinoma. It focuses on evaluating the perioperative outcomes and follow-up results of these two surgical methods. The research will provide evidence-based insights to help determine the best surgical approach for laparoscopic anatomical hemihepatectomy. Participants will be randomly assigned to one of the two surgical techniques during the operation.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 70 with hepatocellular carcinoma who can tolerate laparoscopic surgery and anesthesia.
Not a fit: Patients with severe liver conditions, such as Child-Pugh grade B or C, or those unable to tolerate anesthesia will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and recovery for patients undergoing liver surgery.
How similar studies have performed: Other studies have shown promising results with laparoscopic techniques in liver surgery, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. the site was limited to the patients who were suitable for dissecting hemihepatectomy； 2. the type of disease was limited to hepatocellular carcinoma； 3. the patients were generally able to tolerate anesthesia, the liver reserve function was good, and the patients were suitable for laparoscopic surgery； 4. child-pugh grade A, no severe liver cirrhosis, portal hypertension, no extrahepatic and extrahepatic metastasis and main vascular invasion； 5. the subjects who participated in this study indicated that they were willing to accept the two surgical methods and agreed to be randomly divided into groups during the operation； 6. 18 ≤ age ≤ 70, male or female. Exclusion Criteria: 1. preoperative liver function Child-pugh grade B or C; 2. patients with poor general condition and could not tolerate pneumoperitoneum or anesthesia; 3. patients with severe liver cirrhosis, portal hypertension and lesions invading liver porta; 4. patients with other treatment methods such as radio frequency ablation in addition to dissecting hepatectomy; 5. repeated abdominal operations resulting in severe abdominal adhesion, unable to perform laparoscopic hepatectomy; male and female are not limited
Where this trial is running
Chongqing, Chongqing
- Southwest Hospital — Chongqing, Chongqing, China (Recruiting)
Study contacts
- Study coordinator: Shuguo Zheng, M.D.
- Email: shuguozh@yahoo.com.cn
- Phone: 0086-13508308676
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.