Comparing two irrigation methods before repairing tooth perforations
Effect of Two Irrigation Protocols Applied Prior to Furcation Repair on Post Operative Pain and Healing (A Randomized Clinical Trial)
This study is testing two different ways to clean tooth holes before fixing them to see if one method helps people with old tooth problems heal better and feel less pain.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Minia University Academic / other |
| Locations | 1 site (Minya) |
| Trial ID | NCT06757660 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of two different irrigation protocols applied prior to the repair of furcation defects in mandibular molars. The study focuses on the use of chitosan, a biopolymer known for its antibacterial properties, in conjunction with mineral trioxide aggregate (MTA) to enhance healing outcomes. Patients with old furcation perforations will be treated, and their pain levels and healing progress will be monitored to determine the efficacy of the irrigation methods. The trial aims to provide insights into improving endodontic treatment success rates.
Who should consider this trial
Good fit: Ideal candidates are patients with old furcation perforations in mandibular molars measuring 1 to 2 mm.
Not a fit: Patients requiring post-retained restorations, immunocompromised individuals, pregnant women, smokers, and those with recent antibiotic or analgesic use may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved healing and reduced pain for patients undergoing endodontic treatment for furcation defects.
How similar studies have performed: Previous studies have shown promising results using similar approaches with chitosan and MTA in dental treatments, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with old furcation perforation of mandibular molar. * Size of perforation should be of average 1 to 2 mm. * Period till treatment should be done within one month. * Presence of polyp at the site of perforation is required in this study. Exclusion Criteria: * Teeth in need for post retained restoration. * Immunocompromised patients. * Pregnant women and smokers. * Patients with a history of antibiotic or analgesics intake within the few days before the intervention and cases with previously initiated endodontic treatment.
Where this trial is running
Minya
- Minia University, Faculty of Dentistry — Minya, Egypt (Recruiting)
Study contacts
- Study coordinator: Shreef Mostafa Ibrahim, M.D
- Email: shreefmaklad@yahoo.com
- Phone: +201006792223
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.