Comparing two imaging techniques for detecting right-sided colon polyps during screening colonoscopy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study is a randomized controlled crossover trial aimed at determining whether narrow band imaging (NBI) or white light endoscopy (WLE) is more effective in detecting right-sided colonic polyps in asymptomatic individuals undergoing screening colonoscopy. The research addresses the challenge of missed colorectal adenomas, particularly in the proximal colon, where detection rates are lower. Participants will first undergo WLE followed by NBI to compare the adenoma detection rates between the two methods. The study seeks to enhance colonoscopy performance and improve early detection of colorectal cancer.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Asymptomatic subjects undergoing screening colonoscopy
* age \> 50.
* average risk subjects defined as those without a personal history of inflammatory bowel disease, colon adenoma or cancer or family history of FAP or Familial non-polyposis syndrome or first degree relatives having diagnosed to have colo-rectal carcinoma, no colonoscopy in past 5 years and, ability to provide a written consent to trial participation

Exclusion Criteria:

* unable to consent

Where it's running

• Westmead Hospital
  Sydney, New South Wales, Australia Recruiting

Study contacts

• Study coordinator: Michael Bourke, MBBS
• Phone: 8890555

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.