Comparing two filling techniques for root canal treatments
Sopravvivenza e Healing Rate di Due Tecniche di Otturazione Canalare: Studio Clinico Randomizzato
This study tests whether a new bioceramic sealer works better than a traditional epoxy resin-based sealer for root canal treatments in healthy adults with dental issues.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | University of Bologna Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Bologna) |
| Trial ID | NCT06252337 on ClinicalTrials.gov |
What this trial studies
This clinical study evaluates the effectiveness of a new bioceramic sealer in root canal treatments compared to a traditional epoxy resin-based sealer. Healthy patients aged 18-75 with endodontic issues were enrolled and treated at the University of Bologna. The study involved taking periapical X-rays at various intervals to assess healing and survival rates, with evaluations conducted by trained professionals. The research adheres to ethical guidelines and aims to provide insights into the best practices for endodontic treatment.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 18-75 with endodontic pathology requiring root canal treatment.
Not a fit: Patients with significant structural damage to their teeth or systemic conditions affecting healing may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve healing rates and outcomes for patients undergoing root canal treatments.
How similar studies have performed: Previous studies have shown promising results with bioceramic sealers in endodontics, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age 18-75 years 2. Healthy status (ASA 1 or 2) 3. At least one tooth affected by endodontic pathology (pulpitis, pulp necrosis, re-exacerbated lesions with a previous root canal treatment) (b) Exclusion Criteria: 1. Teeth with less than 2 walls of crown structural integrity 2. Teeth used as abutments for fixed rehabilitation 3. Presence of active periodontal disease (PPD \> 4 mm, general BoP \> 25% of the sites) 4. Wide apexes (\>40 diameters) or absence of radiographic pulp chamber 5. Any systemic pathology that could compromise bone healing or the immune response (i.e., diabetes) 6. Pregnancy or breastfeeding 7. Heavy smoking (\>15 cigarettes/day) 8. Exposure to radiation therapy focused on the head and neck region and malignant disease directly involving the jaws. 9. Lack of occlusal contacts
Where this trial is running
Bologna
- Endodontic clinical section, DIBINEM, UNiversity of Bologna — Bologna, Italy (Recruiting)
Study contacts
- Study coordinator: Fausto Zamparini
- Email: fausto.zamparini2@unibo.it
- Phone: 3471426659
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.