Comparing two exercise methods for knee osteoarthritis

Comparison of Progressive Motor Imagery and Sensorimotor Exercises in Knee Osteoarthritis: A Randomized Controlled Trial

Not applicable Interventional Istanbul Medipol University Hospital · NCT05850793

This study tests which exercise method, Progressive Motor Imagery or Sensorimotor Exercises, helps adults with knee osteoarthritis feel less pain and improve their balance and function.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment54 (estimated)
Ages50 Years to 65 Years
SexAll
SponsorIstanbul Medipol University Hospital Academic / other
Locations1 site (Fatih, Istanbul)
Trial IDNCT05850793 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of Progressive Motor Imagery and Sensorimotor Exercises in patients with knee osteoarthritis. It aims to determine which approach better improves pain, function, and balance in individuals diagnosed with this condition. Participants will engage in either type of exercise program, focusing on rehabilitation through brain exercise and neuromuscular training. The study includes adults aged 50 to 65 with specific criteria related to their osteoarthritis severity and pain levels.

Who should consider this trial

Good fit: Ideal candidates are adults aged 50 to 65 diagnosed with stage 2 or 3 knee osteoarthritis and experiencing moderate pain.

Not a fit: Patients with additional knee pathologies, recent physiotherapy, or significant cardiovascular issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide patients with more effective rehabilitation strategies for managing knee osteoarthritis.

How similar studies have performed: Previous studies have shown positive outcomes with similar rehabilitation approaches, indicating potential for success in this study.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosed with knee OA according to the criteria of the American Society of Rheumatology (ACR),
* Stage 2 or 3 according to Kellgren Lawrence radiological staging criteria,
* Between the ages of 50 and 65,
* Body mass index below 35 kg/m²,
* Pain intensity defined by the patient in the last 3 months is at least 3 out of 10 according to NPRS,
* There are no obstacles to being included in the exercise program,
* Patients with a score of at least 24 on the Standardized Mini Mental Test will be included.

Exclusion Criteria:

* Receiving any physiotherapy program or injection treatment in the last 3 months,
* Having a diagnosis of additional pathology other than OA in the knee, having a history of knee injury / surgery in the past
* Having uncontrollable hypertension, cardiovascular and neurological diseases that will prevent exercise,
* The patient has any vision, hearing or cognitive problems that will prevent him from complying with the treatment,
* Providing ambulation with an assistive device

Where this trial is running

Fatih, Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Osteoarthritis, Kneerehabilitationmotor imagery trainingsensorimotor trainingbalancefunctional performance
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.