Comparing two epidural techniques for labor pain relief
Dural Puncture Epidural Vs Standard Epidural Technique in Parturient Receiving Continuous Labour Epidural Infusion: a Randomized Controlled Trial
NA · Aga Khan University · NCT06653036
This study tests which of two epidural techniques provides better pain relief for women in labor.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 38 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | Aga Khan University (other) |
| Locations | 1 site (Karachi, Sindh) |
| Trial ID | NCT06653036 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness and safety of two different epidural techniques—Dural puncture epidural and Standard epidural technique—in providing continuous labor analgesia for women in labor. It aims to assess the quality of pain relief, the frequency of catheter adjustments, the need for catheter replacements, and the incidence of failed regional anesthesia that may require conversion to general anesthesia. The study focuses on parturient women who are experiencing established labor and have a pain score of 3 or higher.
Who should consider this trial
Good fit: Ideal candidates for this study are nulliparous or multiparous women aged over 18 years, with a singleton vertex presentation and gestational age between 37 to 42 weeks, who are in established labor with a pain score of 3 or higher.
Not a fit: Patients with major cardiac disease, chronic pain, or those on anticoagulants will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve labor pain management and enhance the overall childbirth experience for women.
How similar studies have performed: Previous studies comparing different epidural techniques have shown varying degrees of success, indicating that this approach is relevant but may still yield novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Nulliparous / Multiparous women * Age \>18 years * ASA 1 \& 2 * Singleton vertex presentation * Gestational age 37-42 weeks * Parturient with established labor and pain score ≥ 3 Exclusion Criteria: * Major cardiac disease * History of chronic pain * Chronic opioid user * Platelet count \< 70 x 109/L * spinal cord anomalies * Use of anticoagulants * Allergic to local anesthetics * Patients with preeclampsia/ eclampsia * Known fetal anomalies
Where this trial is running
Karachi, Sindh
- Aga Khan University — Karachi, Sindh, Pakistan (RECRUITING)
Study contacts
- Study coordinator: Samina Ismail, MBBS, FCPS
- Email: samina.ismail@aku.edu
- Phone: +922134864331
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Quality Health Care, Quality Labor Analgesia, Maternal Adverse Events