Comparing two electrode positions for heart rhythm restoration in atrial fibrillation
A Randomized Controlled Trial of Anterior-posterior Versus Anterior-lateral Shock Vectors for Electrical Cardioversion of Atrial Fibrillation
This study is testing whether using two different electrode positions during heart rhythm restoration can help people with atrial fibrillation feel better and have more successful treatments.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 1500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | McMaster University Academic / other |
| Locations | 2 sites (Hamilton, Ontario and 1 other locations) |
| Trial ID | NCT05511389 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of two different electrode positions, anteroposterior and anterolateral, during electrical cardioversion for patients with atrial fibrillation or flutter. By optimizing electrode placement, the study aims to enhance the success rate of restoring normal heart rhythm, potentially leading to better health outcomes and reduced healthcare costs. The trial will involve consenting adult patients who are scheduled for non-emergent cardioversion, while excluding those with contraindications or insufficient anticoagulation. The goal is to determine which electrode position yields superior results in terms of restoring sinus rhythm.
Who should consider this trial
Good fit: Ideal candidates are consenting adult patients scheduled for non-emergent electrical cardioversion of atrial fibrillation or flutter.
Not a fit: Patients who are not adequately anticoagulated or have anatomical contraindications for electrode placement may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved heart rhythm restoration and better overall health outcomes for patients with atrial fibrillation.
How similar studies have performed: While there is ongoing research in optimizing electrical cardioversion techniques, this specific comparison of electrode positions is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Consenting adult patients scheduled for non-emergent electrical cardioversion of Atrial Fibrillation or Flutter Exclusion Criteria: 1. Insufficiently anticoagulation for cardioversion as per Canadian Cardiovascular Society guidelines or have not undergone trans-esophageal echocardiography to rule out left atrial thrombus 2. Anatomic contraindication to anterolateral or anteroposterior placement (e.g. skin conditions or wounds)
Where this trial is running
Hamilton, Ontario and 1 other locations
- Hamilton Health Sciences — Hamilton, Ontario, Canada (Recruiting)
- St Joseph's Healthcare Hamilton — Hamilton, Ontario, Canada (Recruiting)
Study contacts
- Study coordinator: William McIntyre, MD
- Email: william.mcintyre@phri.ca
- Phone: 9055212100
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.