Comparing two daily myopia-control contact lenses for Chinese children in New Zealand
The Effect of Myopia-Control Contact Lenses in New Zealand Chinese Children
PHASE3 · Aston University · NCT07535749
This trial will test whether daily MiSight or Abiliti contact lenses slow myopia progression in Chinese children aged 7–11 in Auckland, New Zealand.
Quick facts
| Phase | PHASE3 |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 7 Years to 11 Years |
| Sex | All |
| Sponsor | Aston University (other) |
| Locations | 1 site (Auckland) |
| Trial ID | NCT07535749 on ClinicalTrials.gov |
What this trial studies
This is a randomized, controlled, investigator-masked paired-eye comparison where each child wears a different myopia-control daily lens in each eye (MiSight 1 Day versus Abiliti 1-Day) for 6 months. Participants will be seen at baseline, 2 weeks, 3 months, and 6 months with standard clinical assessments of refraction and axial length. The study plans to recruit about 53–66 New Zealand Chinese children aged 7–11 with mild to moderate myopia and low astigmatism. All visits take place at the Auckland Myopia Clinic and follow routine pediatric myopia care, the only change being the randomized lens assignment between eyes.
Who should consider this trial
Good fit: Ideal candidates are Chinese children in New Zealand aged 7–11 with spherical myopia between −1.00 D and −4.50 D, ≤1.00 D astigmatism, no prior orthokeratology or atropine use, and no ocular disease or surgery history.
Not a fit: Children outside the age or prescription range, with higher astigmatism, prior orthokeratology or atropine treatment, or existing ocular disease are unlikely to benefit from this specific comparison.
Why it matters
Potential benefit: If successful, one of the lenses could better slow eye growth and reduce the long-term risk of high myopia and its complications for children.
How similar studies have performed: Previous randomized trials of myopia-control soft contact lenses, including studies of MiSight, have shown reductions in axial elongation and refractive progression, though devices and magnitudes of effect vary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Spherical refractive error between -1.00D and -4.50D * Astigmatism of ≤1.00D * No history of orthokeratology or atropine use * No ocular diseases or surgical history Exclusion Criteria: o No ocular diseases or surgical history
Where this trial is running
Auckland
- Auckland Myopia Clinic — Auckland, New Zealand (RECRUITING)
Study contacts
- Study coordinator: James S Wolffsohn, BSc PhD DSc
- Email: j.s.w.wolffsohn@aston.ac.uk
- Phone: +447833049245
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Myopia Progression, myopia control, contact lenses