Comparing two collagen membranes for dental implant bone augmentation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of two types of collagen membranes used during bone augmentation procedures for dental implants. Participants will receive an implant with simultaneous bone augmentation and will be monitored for bone stability and the occurrence of ceramic restoration chipping over a period of five years. The study will evaluate whether a new compressed collagen membrane provides better bone stability compared to a standard membrane. The trial focuses on patients needing a single tooth replacement in the aesthetic zone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Informed Consent signed by the subject
* ≥18 years of age
* No active periodontal disease
* Full-mouth plaque score and full-mouth bleeding score \<25%.
* Patients in need of an implant-supported crown at a single-tooth gap in the aesthetic region: 11-15, 21-25, 31-35, 41-45 (FDI)
* Patients in need of GBR during implant placement (1-stage procedure)
* Presence of mesial and distal natural teeth or implant
* Implant placement at least 6 weeks after tooth extraction
* No need for soft tissue grafting

Exclusion Criteria:

* Any conditions or circumstances which would interfere with the requirements for oral surgery
* Patients with large bone defects, in need of a primary bone augmentation (two-stage procedure)
* Allergy to any implant metallic component
* Allergy to collagen
* Previous oral-maxillo-facial radiotherapy
* Any disorders in the planned implant area such as previous tumors, chronic bone
* disease (such as rheumatoid disease)
* Any ongoing application of interfering medication (steroid therapy, bisphosphonate, etc.)
* Alcohol or drug abuse
* No need for soft tissue grafting
* Patients with inadequate oral hygiene or persistent oral infection
* Clinically significant concomitant diseases (e.g. renal failure, hepatic disfunction, cardiovascular diseases)
* Heavy smokers (\>10 cigarettes/day)
* Uncontrolled diabetes
* Severe bruxism or other destructive habits
* Pregnant or lactating women

Where it's running

• University of Geneva
  Geneva, Canton of Geneva, Switzerland Recruiting

Study contacts

• Principal investigator: Malin Strasding, Dr dent med — University Clinic of Dental Medicine, University of Geneva
• Study coordinator: Malin Strasding, Dr dent med
• Email: malin.strasding@unige.ch
• Phone: +41 (0)22 379 40 50

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.