Comparing two bone augmentation techniques for the anterior maxilla

Radiographic and Histological Assessment of Retromolar Autogenous Onlay Bone Block Versus Cortical Shell for Augmentation of Horizontally Deficient Anterior Maxilla: (Randomized Clinical Trial).

This study is testing two different ways to add bone to the front of the upper jaw in patients who need it, to see which method works better for healing.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 16 (estimated)
• Ages: 20 Years to 60 Years
• Sex: All
• Sponsor: Cairo University (other)
• Locations: 1 site (Cairo, Giza Governorate)
• Trial ID: NCT06450535 on ClinicalTrials.gov

What this trial studies

This clinical trial involves two groups of patients with horizontally deficient anterior maxilla who require bone augmentation. One group will receive an autogenous onlay bone block harvested from the retromolar area, while the other group will undergo a cortical shell technique also using retromolar bone. Prior to the procedures, patients will receive periodontal therapy and oral hygiene instructions. The surgical approach includes local anesthesia, flap creation, and careful harvesting of bone to ensure optimal graft adaptation and healing.

Who should consider this trial

Good fit: Ideal candidates are patients aged 20 to 60 with partial edentulism in the maxilla and a residual ridge width of less than 4 mm.

Not a fit: Patients with systemic conditions, poor oral hygiene, or those who have undergone recent irradiation in the head and neck area may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve bone augmentation techniques, leading to better outcomes for patients requiring dental implants in the anterior maxilla.

How similar studies have performed: While similar techniques have been explored, this specific comparison of autogenous onlay bone block versus cortical shell in the anterior maxilla is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Patients in both sex with partial edentulism of the maxilla and requiring horizontal ridge augmentation
* The ages of the patients ranged from 20 to 60 years.
* The residual ridge width in these patients are less than 4.m
* Sufficient bone in intra-oral donor sites are available (external oblique ridge)
* Patients free from any systemic conditions and bone metabolism diseases that might interfere with the surgical intervention, soft tissue or hard tissue healing.
* The vertical level should be in a favourable esthetic appearance with normal inter-arch space
* The minimum number of missing teeth in the anterior maxilla alveolar ridge is one single extracted teeth

Exclusion Criteria:

* Subjected to irradiation in the head and neck area less than 1 year before implantation.
* Poor oral hygiene and motivation.
* Uncontrolled diabetes.
* Pregnant or nursing.
* Substance abuse.
* Psychiatric problems or unrealistic expectations.
* Severe bruxism or clenching.
* Immunosuppressed or immunocompromised.

Where this trial is running

Cairo, Giza Governorate

• faculty of oral and dental medicine ,Cairo university — Cairo, Giza Governorate, Egypt (RECRUITING)

Study contacts

• Study coordinator: maria ibrahim nageeb, BSc

Conditions: Alveolar Bone Loss, Autogenous onlay bone block, Cortical shell technique