Comparing two biopsy methods for diagnosing sarcoidosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the diagnostic yield of endobronchial cryobiopsy versus forceps biopsy in patients suspected of having pulmonary sarcoidosis. A total of 150 patients will be randomized into two groups, with each group undergoing one of the biopsy methods during a routine endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The primary outcome is to determine the proportion of successful diagnoses between the two techniques. Biopsy samples will be processed and analyzed to confirm the presence of non-caseating granulomas characteristic of sarcoidosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

All patients of suspected pulmonary sarcoidosis scheduled for routine EBUS-TBNA

Exclusion Criteria:

1. Patient age less than 18 years
2. Patients with co-morbid conditions like Diabetes mellitus, renal failure, chronic liver disease or any other chronic disease.
3. Patients already on treatment with steroids or h/o steroids intake in last three months or on disease modifying and immunosuppressive drugs.
4. Final Diagnosis other than sarcoidosis

Where it's running

• Sanjay Gandhi Postgraduate Institute of Medical Sciences
  Lucknow, Uttar Pradesh, India Recruiting

Study contacts

• Principal investigator: Ajmal Khan, MBBS, MD, DM — Sgpgims
• Study coordinator: Ajmal Khan, MBBS, MD, DM
• Email: drajmal13@gmail.com
• Phone: +919878678689

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Exploring genetic factors in lung disease development

  This study is trying to find out how certain genes might play a role in lung diseases like cystic fibrosis and asthma by looking at lung cells from both patients and healthy people.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland and 1 other locations · NCT00001532

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.