Comparing two anesthesia techniques for dental implant placement

Comparison of Anesthetic Efficacy and Safety Between Nerve Block and Infiltrative Technique for Mandibular Posterior Implant Placement. a Triple-blind Randomized Clinical Trial.

Not applicable Interventional University of Barcelona · NCT06641232

This study is testing which of two anesthesia methods works better and is safer for adults getting dental implants in the back of their mouths.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment42 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Barcelona Academic / other
Locations1 site (L'Hospitalet de Llobregat, Barcelona)
Trial IDNCT06641232 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the safety and effectiveness of two anesthesia techniques, the inferior dental nerve block (IDNB) and the infiltrative technique (TINF), during the placement of mandibular posterior dental implants in patients with partial edentulism. It is a triple-blind randomized trial that will measure outcomes such as the need for reanesthesias, rates of adverse effects, and levels of postoperative pain. The study will involve adult patients who meet specific eligibility criteria and will assess their dental anxiety prior to the procedure.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who are partially edentulous and require mandibular implants in the molar area.

Not a fit: Patients who are pregnant, have allergies to the anesthetics used, or have uncontrolled systemic diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management and safety in dental implant procedures.

How similar studies have performed: Previous studies have shown varying results regarding the efficacy of different anesthesia techniques in dental procedures, making this approach both relevant and necessary.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of legal age (≥18 years), partially edentulous, requiring the placement of one or more mandibular implants in the molar area.
* Patients without relevant systemic pathology (equal or lower than ASA II).
* Sufficient intellectual capacity to understand the study, the informed consent and to adequately complete the questionnaires.

Exclusion Criteria:

* - Pregnant patients.
* Patients with allergy or hypersensitivity to articaine or adrenaline.
* Patients with uncontrolled systemic diseases.
* Patients who may recognize the anesthetic technique used (e.g. dentists).
* Drugs or systemic diseases (ASA III or higher) that contraindicate surgical intervention or the use of anesthetics and/or vasoconstrictors.
* Patients with relative or absolute contraindication of conventional analgesic or anti-inflammatory regimen.
* Immediate implants.
* Surgeries requiring bone grafts.

Where this trial is running

L'Hospitalet de Llobregat, Barcelona

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Dental ImplantsLocal Anesthesiadental implantslocal anesthesiablock nerve
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.