Comparing treatments for tooth extraction in the aesthetic area
Management of the Fresh Extraction Socket in the Aesthetic Area: Alveolar Ridge Preservation vs Immediate Implant Placement vs Delayed Implant Placement
This study is testing three different ways to treat the area after a tooth extraction to see which method works best for getting dental implants in the front of the mouth.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centro Specialistico Odontoiatrico, Rome Research network |
| Drugs / interventions | radiation |
| Locations | 1 site (Roma) |
| Trial ID | NCT04367766 on ClinicalTrials.gov |
What this trial studies
This study evaluates three different treatment approaches following tooth extraction in the aesthetic zone: immediate implant placement with provisionalization, alveolar ridge preservation followed by delayed implant placement, and spontaneous healing before implant placement. Patients will be randomly assigned to one of these groups, and their outcomes will be assessed over a period of five years. Key metrics include patient-related outcomes, cost-effectiveness, and changes in bone and soft tissue volume. The study aims to provide insights into the best management strategies for dental implants in aesthetic areas.
Who should consider this trial
Good fit: Ideal candidates are adults requiring single tooth extraction in the anterior region with good periodontal health and adequate bone quality.
Not a fit: Patients with autoimmune diseases, uncontrolled diabetes, or those who have undergone head and neck radiation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve patient outcomes and satisfaction in dental implant procedures following tooth extraction.
How similar studies have performed: Previous studies have shown varying success with similar approaches, but this specific comparison of treatment modalities is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * single tooth extraction in the anterior region of the dentition (including premolars) to be extracted * smoking no more than 10 cigarettes/day, * periodontal health (BoP \< 10%) and good plaque control (\< 20%) * absence of symptomatic periapical radiolucencies, acute abscesses at the site of extraction, * extraction sites with less than 30% loss of one or more walls * adequate quantity and quality of native bone to achieve primary stability Exclusion Criteria: * growing patients * patients with autoimmune disease, uncontrolled diabetes or immunocompromised * history of head and neck radiation for cancer treatment, * pregnancy
Where this trial is running
Roma
- Centro Specialistico Odontoiatrico (CSO) — Roma, Italy (Recruiting)
Study contacts
- Principal investigator: Marco Clementini, DDS, PhD — Centro Specialistico Odontoiatrico, Rome
- Study coordinator: Marco Clementini, DDS, PhD
- Email: mclementini@me.com
- Phone: 00393388378866
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.