Comparing treatments for simple bone cysts in children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to compare the effectiveness of two common treatments for simple bone cysts (SBCs) in children, specifically curettage with puncture alone versus curettage with puncture followed by injection with Vitoss morsels. SBCs are fluid-filled cysts that commonly occur in the long bones of children and can cause pain and functional limitations. The study will assess the rate of radiographic healing, identify prognostic factors associated with healing and fractures, and evaluate the impact of SBCs on children and their families. By utilizing a network of surgeons and researchers, the trial seeks to provide evidence-based insights into the best treatment options for SBCs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with a confirmed simple bone cyst in a long bone (ie. arm or leg) within last 3 months
* At least 3 weeks must have elapsed since last fracture
* At least 3 months must have elapsed since last cyst treatment
* Patients and/or their legal representatives willing to provide written informed consent (and assent, when appropriate)
* Patients with stabilizing implants in the bone where the cyst is located

Exclusion Criteria:

* Patients with bone disease (ie. osteogenesis imperfecta, cancer, osteoporosis, Paget's disease)
* Pregnant or breastfeeding female
* Patients with cysts crossing the growth plate (area where bone grows)

Where it's running

• Loma Linda University
  Loma Linda, California, United States Recruiting
• Ann & Robert H. Lurie Children's Hospital of Chicago
  Chicago, Illinois, United States Recruiting
• University of North Carolina - Chapel Hill
  Chapel Hill, North Carolina, United States Recruiting
• Texas Children's Hospital
  Houston, Texas, United States Recruiting
• The Royal Children's Hospital
  Melbourne, Australia Recruiting
• Alberta Children's Hospital
  Calgary, Alberta, Canada Recruiting

Study contacts

• Principal investigator: James G. Wright — The Hospital for Sick Children
• Study coordinator: Project Manager
• Email: sbock.study@sickkids.ca

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.