Clinical trial Recruiting at 1 site Interventional Ages 6 to 65

Comparing treatments for reducing dark circles caused by rhinitis

Official title: Camillian Saint Mary's Hospital Luodong

Run by Camillians Saint Mary's Hospital Luodong · NCT05348148 · Data updated 2026-11-12

This study is testing different treatments for people with rhinitis to see which one best helps reduce dark circles under the eyes caused by nasal congestion.

Quick facts

Study typeInterventional
Ages6 Years to 65 Years
SexAll
Enrollment450 (estimated)
SponsorCamillians Saint Mary's Hospital Luodong
Academic / other
Locations1 site (Luodong, Yilan)
StatusRecruiting
StartedJune 16, 2020
Main results expectedMarch 31, 2032
Study endsMarch 31, 2032
Registry record updatedApril 27, 2022
Trial IDNCT05348148 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 6 to 65 with a clinical diagnosis of moderate to severe allergic or non-allergic rhinitis.

Probably not a fit

Patients with chronic rhinosinusitis, recent facial trauma, malignancies, or those currently pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of various treatments for allergic and non-allergic rhinitis in reducing the appearance of shiners, which are dark circles under the eyes caused by nasal congestion. Participants aged 6 to 65 will be randomly assigned to receive different treatment combinations, including oral antihistamines and intranasal corticosteroids. The primary goal is to determine which treatment most effectively alleviates shiners, while secondary outcomes will assess the overall impact on rhinitis symptoms. The study employs a randomized controlled design to ensure reliable results.

Why it matters

Potential benefit: If successful, this study could provide effective treatment options for patients suffering from rhinitis and associated shiners, improving their quality of life.

How similar studies have gone: While there have been studies on rhinitis treatments, this specific focus on shiners is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of moderate to severe rhinitis, either allergic rhinitis or non-allergic rhinitis.

Exclusion Criteria:

* Chronic rhinosinusitis
* Trauma to the forehead or nose
* Face surgery
* Malignancy
* Pregnancy
* Respiratory tract infections within a week before beginning the study
* Usage of medications for rhinitis within a week before beginning the study

Where it's running

  • Camillian Saint Mary's Hospital Luodong
    Luodong, Yilan, Taiwan
    Recruiting

Study contacts

  • Principal investigator: Cheng-Tsung Yang — Camillian Saint Mary's Hospital Luodong
  • Study coordinator: Cheng-Tsung Yang
  • Email: jjbulebeer@gmail.com
  • Phone: 886+926436056

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.