Comparing treatments for reducing dark circles caused by rhinitis

Camillian Saint Mary's Hospital Luodong

Not applicable Interventional Camillians Saint Mary's Hospital Luodong · NCT05348148

This study is testing different treatments for people with rhinitis to see which one best helps reduce dark circles under the eyes caused by nasal congestion.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment450 (estimated)
Ages6 Years to 65 Years
SexAll
SponsorCamillians Saint Mary's Hospital Luodong Academic / other
Locations1 site (Luodong, Yilan)
Trial IDNCT05348148 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of various treatments for allergic and non-allergic rhinitis in reducing the appearance of shiners, which are dark circles under the eyes caused by nasal congestion. Participants aged 6 to 65 will be randomly assigned to receive different treatment combinations, including oral antihistamines and intranasal corticosteroids. The primary goal is to determine which treatment most effectively alleviates shiners, while secondary outcomes will assess the overall impact on rhinitis symptoms. The study employs a randomized controlled design to ensure reliable results.

Who should consider this trial

Good fit: Ideal candidates include individuals aged 6 to 65 with a clinical diagnosis of moderate to severe allergic or non-allergic rhinitis.

Not a fit: Patients with chronic rhinosinusitis, recent facial trauma, malignancies, or those currently pregnant may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide effective treatment options for patients suffering from rhinitis and associated shiners, improving their quality of life.

How similar studies have performed: While there have been studies on rhinitis treatments, this specific focus on shiners is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Clinical diagnosis of moderate to severe rhinitis, either allergic rhinitis or non-allergic rhinitis.

Exclusion Criteria:

* Chronic rhinosinusitis
* Trauma to the forehead or nose
* Face surgery
* Malignancy
* Pregnancy
* Respiratory tract infections within a week before beginning the study
* Usage of medications for rhinitis within a week before beginning the study

Where this trial is running

Luodong, Yilan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Allergic RhinitisVasomotor Rhinitisshinersrhinitis
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.