Comparing treatments for Plantar Fasciitis using collagen peptides and ESWT
Official title: Comparison of ESWT and Collagen Hydrolyzed Peptides in the Treatment of Plantar Fascitiis
Run by Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · NCT06138236 · Data updated 2026-11-12
This study is testing whether collagen peptides, shock wave therapy, or a mix of both can help people with plantar fasciitis feel less pain and improve their foot function.
Quick facts
| Phase | Early Phase 1 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari Academic / other |
| Locations | 1 site (Bari) |
| Status | Recruiting |
| Started | July 1, 2023 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | December 8, 2025 |
| Trial ID | NCT06138236 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 to 80 who are diagnosed with Plantar Fasciitis.
✕Probably not a fit
Patients who have previously undergone foot surgery or have contraindications to ESWT may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of two treatments for Plantar Fasciitis: infiltration of Collagen Hydrolyzed Peptides and Extracorporeal Shock Wave Therapy (ESWT). Patients are randomized into three groups, receiving either treatment alone or a combination of both. The outcomes are measured using the Numeric Rating Scale (NRS) and the Ankle Function Assessment Scale (AFAS) to evaluate pain and functional improvement. The goal is to determine which treatment or combination yields the best results for patients suffering from this condition.
Why it matters
Potential benefit: If successful, this study could provide effective treatment options for patients suffering from Plantar Fasciitis, potentially improving their quality of life.
How similar studies have gone: While there have been studies on ESWT and collagen treatments separately, this specific comparison of both approaches is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Plantar fascitiis Aged between 18 and 80 years old Exclusion Criteria: * Previous surgery of the foot * Contraindications to ESWT
Where it's running
-
Angela Notarnicola
Bari, Italy Recruiting
Study contacts
- Principal investigator: Silvana DE GIORGI, PI — University of Bari
- Study coordinator: Silvana DE GIORGI, PI
- Email: silvana.degiorgi@uniba.it
- Phone: 3389821930
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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F-18 PET/CT-Guided Lu-177 Therapy Added to Corticosteroid Injections for Chronic Plantar Fasciitis
This study tests whether adding a low-dose Lu-177 therapy guided by F-18 NaF PET/CT to standard corticosteroid injections helps relieve pain and improve function in adults with chronic plantar fasciitis who didn’t improve with conservative care.
-
Video-guided vs physician-led exercise training for plantar fasciitis
This trial tests whether a standardized video-based exercise program works as well as in-person instruction by a physician for adults with plantar fasciitis.
-
Deep transverse friction massage versus instrument-assisted soft tissue mobilization for pregnancy-related plantar fasciitis
This test compares deep transverse friction massage and instrument-assisted soft tissue mobilization to see which better reduces heel pain and improves walking for pregnant women with plantar fasciitis.
-
Dissolvable SakuraBead embolization for plantar fascia pain
This trial will try dissolvable SakuraBead embolization in adults with plantar fasciitis to see if it reduces heel pain better than shockwave therapy.
-
Effects of dry needling combined with physical therapy on plantar fasciitis
This study is testing if combining dry needling with regular physical therapy can help people aged 40-60 with chronic heel pain feel better and move more easily compared to just doing physical therapy alone.
-
Comparing IASTM and Kinesiotaping for Plantar Fasciitis
This study is testing whether a hands-on treatment called IASTM or a supportive taping method works better to help people aged 20-40 with chronic heel pain from plantar fasciitis feel better and improve their foot function.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.