Comparing treatments for Plantar Fasciitis using collagen peptides and ESWT

Comparison of ESWT and Collagen Hydrolyzed Peptides in the Treatment of Plantar Fascitiis

Early Phase 1 Interventional Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari · NCT06138236

This study is testing whether collagen peptides, shock wave therapy, or a mix of both can help people with plantar fasciitis feel less pain and improve their foot function.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Enrollment84 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorAzienda Ospedaliero-Universitaria Consorziale Policlinico di Bari Academic / other
Locations1 site (Bari)
Trial IDNCT06138236 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of two treatments for Plantar Fasciitis: infiltration of Collagen Hydrolyzed Peptides and Extracorporeal Shock Wave Therapy (ESWT). Patients are randomized into three groups, receiving either treatment alone or a combination of both. The outcomes are measured using the Numeric Rating Scale (NRS) and the Ankle Function Assessment Scale (AFAS) to evaluate pain and functional improvement. The goal is to determine which treatment or combination yields the best results for patients suffering from this condition.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 80 who are diagnosed with Plantar Fasciitis.

Not a fit: Patients who have previously undergone foot surgery or have contraindications to ESWT may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide effective treatment options for patients suffering from Plantar Fasciitis, potentially improving their quality of life.

How similar studies have performed: While there have been studies on ESWT and collagen treatments separately, this specific comparison of both approaches is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Plantar fascitiis Aged between 18 and 80 years old

Exclusion Criteria:

* Previous surgery of the foot
* Contraindications to ESWT

Where this trial is running

Bari

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Plantar Fascitis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.