Comparing treatments for non-invasive prolactinoma
Prospective Randomized Clinical Study on Transsphenoidal or Dopamine Drugs Therapy Treat Non-invasive Prolactinoma
This study is testing whether surgery or medication works better to help people with non-invasive prolactinoma feel better and achieve hormonal balance.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 394 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital, Sun Yat-Sen University Academic / other |
| Locations | 1 site (Guangzhou) |
| Trial ID | NCT03353025 on ClinicalTrials.gov |
What this trial studies
This study investigates the endocrine remission rates of non-invasive prolactinoma patients treated with either transsphenoidal surgery or dopamine agonist therapy. The aim is to determine which treatment is more effective in achieving remission. By comparing these two approaches, the study seeks to clarify the ongoing debate regarding the best management strategy for non-invasive prolactinomas. Participants will be monitored for their hormonal levels and clinical outcomes following treatment.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with non-invasive prolactinoma.
Not a fit: Patients with invasive prolactinoma will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide clearer guidance on the most effective treatment for non-invasive prolactinoma, potentially improving patient outcomes.
How similar studies have performed: While there have been studies on prolactinoma treatments, this specific comparison of surgical versus medical management is less common, making it a potentially novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: non-invasive prolactionma Exclusion Criteria: invasive prolactioma
Where this trial is running
Guangzhou
- Sun Yat-sen 5010 program — Guangzhou, China (Recruiting)
Study contacts
- Study coordinator: Zongming Wang, Dr.
- Email: wzmyan@foxmail.com
- Phone: 8613570903721
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.