Comparing treatments for constipation in children with Hirschsprung allied disease
Official title: A Prospective, Randomized Controlled Trial of Conservative Versus Surgery Treatment of Children With Hirschsprung Allied Disease
Run by Tongji Hospital · NCT02212054 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether non-surgical treatments or surgery work better to help children with Hirschsprung allied disease manage their constipation.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 1 Year to 14 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Tongji Hospital Academic / other |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT02212054 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are children experiencing hard or firm stools twice or less per week and who have a predicting score of less than 5.
✕Probably not a fit
Patients with functional constipation or a predicting score of more than 5 may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to evaluate the effectiveness of conservative treatments, such as anal dilatation and colonic lavage, versus operative treatments for alleviating constipation symptoms in children diagnosed with Hirschsprung allied disease. The research will involve assessing the frequency and consistency of bowel movements in participants receiving either treatment approach. By comparing these two methods, the study seeks to determine which is more beneficial for improving the quality of life in affected children.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective treatment options for managing constipation in children with Hirschsprung allied disease.
How similar studies have gone: While there may be limited data on similar studies, the comparative approach of conservative versus operative treatments in this specific context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * hard or firm stools for twice or less per week * a predicting score of less than 5 refer to literature: Wu, X.J., et al., A new diagnostic scoring system to differentiate Hirschsprung's disease from Hirschsprung's disease-allied disorders in patients with suspected intestinal dysganglionosis. Int J Colorectal Dis, 2013. 28(5): p. 689-96 Exclusion Criteria: * functional constipation * a predicting score of more than 5 refer to literature: Wu, X.J., et al., A new diagnostic scoring system to differentiate Hirschsprung's disease from Hirschsprung's disease-allied disorders in patients with suspected intestinal dysganglionosis. Int J Colorectal Dis, 2013. 28(5): p. 689-96
Where it's running
-
Department of Pediatric Surgery
Wuhan, Hubei, China Recruiting
Study contacts
- Principal investigator: Qi T Zhu, PhD — department of pediatric surgery
- Study coordinator: Xiong J Feng, MD,PhD
- Email: 31699788@qq.com
- Phone: 0086-27-83665309
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Investigating causes and early detection of infections after major abdominal surgery
This study is trying to find out if germs from the gut and mouth can cause infections after major abdominal surgery in cancer patients, and if certain biological markers can help predict these infections.
-
Evaluating patient-reported complications after digital consent for breast cancer surgery
This study is trying to see if asking breast cancer surgery patients to report their own complications through a digital consent process can help improve how we understand and manage post-surgery issues.
-
Evaluating a new surgical technique for patients with acute type A aortic dissection
This study is testing a new surgical method for people with acute type A aortic dissection to see if it is safer and more effective than the standard technique.
-
Using a J-shaped retromesenteric omental flap to cover exposed arteries during pancreaticoduodenectomy
This study will test whether completely covering exposed peripancreatic arteries with a retromesenteric omental flap during pancreaticoduodenectomy reduces serious post‑operative bleeding in adults at high risk of pancreatic fistula.
-
Comparing techniques for preserving liver grafts from deceased donors
This study is testing three different ways to keep liver donations from deceased donors in good shape to see if any of them can improve their quality and help more patients receive successful transplants.
-
Identifying risk factors and outcomes for patients needing acute surgical care
This study looks at patients who needed emergency surgery to see what factors might lead to complications or death, helping to improve future treatments and care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.