Clinical trial Recruiting at 1 site Observational Ages 18 and up

Comparing transcutaneous and arterial CO2 monitoring during jet ventilation for percutaneous liver tumor ablation

Official title: Transcutaneous Versus Arterial Carbon Dioxide Monitoring During Jet Ventilation

Run by Sahlgrenska University Hospital · NCT07211763 · Data updated 2026-11-12

This project will test whether skin-based (transcutaneous) CO2 monitors give the same readings as arterial blood CO2 in adults having jet ventilation during percutaneous liver tumor ablation.

More Liver Ablation trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorSahlgrenska University Hospital
Academic / other
Locations1 site (Gothenburg)
StatusRecruiting
StartedApril 1, 2025
Main results expectedJune 2026
Study endsJuly 2026
Registry record updatedOctober 8, 2025
Trial IDNCT07211763 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults scheduled for percutaneous radiofrequency liver tumor ablation who require jet ventilation and can give informed consent are the intended participants.

Probably not a fit

Patients not receiving jet ventilation, minors, or those with conditions that make jet ventilation unsafe would not be eligible and would not benefit from this comparison.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

During percutaneous radiofrequency ablation of liver tumors, high-frequency jet ventilation is used to reduce diaphragm movement but prevents standard end-tidal CO2 monitoring. At this single center, patients receive both transcutaneous CO2 monitoring and arterial blood gas sampling as part of routine care, and consenting patients will have those values collected prospectively. The collected paired measurements will be compared using repeat-measures Bland–Altman analysis to quantify agreement and any systematic differences. All patients are managed according to the usual preoperative and intraoperative protocols and participation only involves allowing use of their monitoring data for analysis.

Why it matters

Potential benefit: If transcutaneous monitoring reliably matches arterial CO2, patients could avoid some invasive blood sampling and clinicians would have a noninvasive way to track ventilation during jet ventilation.

How similar studies have gone: Prior work outside jet ventilation has shown reasonable agreement between transcutaneous CO2 and arterial CO2 in other ventilation settings, but data specifically during high-frequency jet ventilation are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult patients undergoing percutaneous RF liver tumour ablation requiring jet ventilation

Exclusion Criteria:

* disease or condition. not compatible with jet ventilation

Where it's running

  • Sahlgrenska University Hospital
    Gothenburg, Sweden
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.