Comparing titanium and soft metal frameworks for dental implants
Titanium Versus Soft Metal CAD/CAM Frameworks for All-on-4 Implant Supported Prosthesis. A Study of Peri-implant Changes and Framework Adaptation
This study is testing whether titanium or soft metal frameworks work better for dental implants in people getting All-on-4 prostheses.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | Male |
| Sponsor | Mansoura University Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Mansoura) |
| Trial ID | NCT06114966 on ClinicalTrials.gov |
What this trial studies
This study compares the effectiveness of titanium frameworks versus soft metal frameworks in mandibular All-on-4 implant-supported prostheses. It evaluates peri-implant soft tissue health, bone level changes around the implants, and framework adaptation using advanced imaging techniques. Twenty patients will be divided into two groups, each receiving a different type of framework, and monitored over 18 months. The study aims to provide insights into which material offers better outcomes for dental prosthetics.
Who should consider this trial
Good fit: Ideal candidates are completely edentulous patients with sufficient mandibular bone height and healthy oral mucosa.
Not a fit: Patients with systemic diseases contraindicating implant placement or those with a history of para-functional habits may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved dental prosthetic outcomes and enhanced patient satisfaction.
How similar studies have performed: While there have been studies comparing different materials for dental implants, this specific comparison of titanium versus soft metal frameworks is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Completely edentulous maxillary and mandibular ridges with sufficient mandibular bone height in the inter-foraminal area confirmed with panoramic x-rays. * All selected patients will be with sufficient inter-arch space and restorative space. * All selected patients will have apparently healthy ridge covered by compressible oral mucosa and free from any ridge flabbiness. Exclusion Criteria: * Patients with systemic diseases that contraindicate implant placement such as hematologic diseases, serious problems of coagulation and diseases of the immune system. Also, metabolic diseases related to bone resorption such as uncontrolled diabetics or osteoporosis will be also excluded * History of para-functional habits (Bruxism, clenching), smoking and alcoholism. * History of radiation therapy in the head and neck region.
Where this trial is running
Mansoura
- Mansoura University, Faculty of dentistry — Mansoura, Egypt (Recruiting)
Study contacts
- Principal investigator: Mohamed Shady, MD — Mansoura University Faculty of Dentistry, Prosthodontics department
- Study coordinator: Mohamed Shady, MD
- Email: Mohamedshady@mans.edu.eg
- Phone: 01005225707
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.