Comparing three devices for airway management during anesthesia

GMA-Tulip, I-gel and the LMA-Supreme (LMA-S) Devices in Airway Management Under General Anesthesia, a Randomized Controlled Study

Not applicable Interventional Zhejiang Cancer Hospital · NCT06383494

This study tests which of three airway devices works best for patients having elective breast or lower abdominal surgery to help them breathe safely during anesthesia.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment498 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorZhejiang Cancer Hospital Academic / other
Locations1 site (Hangzhou, Zhejiang)
Trial IDNCT06383494 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of three supraglottic airway devices (LMA Supreme, I-gel, and GMA-Tulip) in managing the airway of patients undergoing elective breast or lower abdominal surgery. Patients are randomly assigned to one of the three device groups, and their airway management quality is assessed using fiberoptic bronchoscopy to grade glottic exposure. Key metrics such as peak airway pressure, incidence of complications like pharyngalgia and hoarseness, and overall ventilation quality are recorded to determine the best device for airway management.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-75 with ASA physical status I-III, scheduled for elective surgery lasting less than 4 hours.

Not a fit: Patients with a history of oropharyngeal surgery, anatomical abnormalities, or those at high risk for reflux/aspiration may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance airway management techniques, leading to improved patient safety and outcomes during anesthesia.

How similar studies have performed: Previous studies have shown varying success with different supraglottic airway devices, making this approach both relevant and necessary for further exploration.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18-75 years old;
* American Society of Anesthesiologists (ASA) I-III;
* Body mass index (BMI)\<30Kg/m2;
* Scheduled for elective breast or lower abdominal surgery with an estimated duration of less than 4 hours;
* Providing written inform consent.

Exclusion Criteria:

* History of oropharyngeal surgery and anatomical abnormalities;
* Limited movement of the cervical spine;
* High risk of reflux/aspiration;
* Emergency surgery;
* Acute throat inflammation and upper respiratory infection;
* History of chronic bronchitis or asthma;
* Cognitive dysfunction and inability to communicate;
* Participating in other clinical trials.

Where this trial is running

Hangzhou, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AnesthesiaAirway RemodelingSupraglottic airway deviceLaryngeal inlet encapsulationLMA-Supremei-gelFiberoptic alignmentOptimal anatomical position
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.