Comparing three analgesic techniques for lumbar fixation surgery
Official title: EVALUATION OF POSTOPERATIVE EFFECT OF THREE DIFFERENT ANALGESIC TECHNIQUES IN PATIENTS UNDERGOING LUMBAR FIXATION SURGERY USING SALIVARY OPIORPHIN LEVEL: A PROSPECTIVE RANDOMIZED CLINICAL STUDY
Run by Ataturk University · NCT06801574 · Data updated 2026-11-12
This trial tests three ways of controlling pain — including an erector spinae plane block and wound infiltration — for adults having elective lumbar fixation surgery to see if they reduce postoperative pain and opioid use.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 84 (estimated) |
| Sponsor | Ataturk University Academic / other |
| Locations | 1 site (Erzurum) |
| Status | Recruiting |
| Started | February 1, 2025 |
| Main results expected | February 1, 2026 |
| Study ends | March 1, 2026 |
| Registry record updated | October 3, 2025 |
| Trial ID | NCT06801574 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18–65 scheduled for elective lumbar fixation under general anesthesia with ASA I–II status who can use a PCA device and have no contraindication to local anesthetics.
✕Probably not a fit
Patients with ASA III or higher, known allergy to local anesthetics, recent opioid use, smoking or alcohol history, or inability to use PCA are unlikely to benefit from participating.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional trial compares postoperative pain control provided by three different analgesic approaches in adults undergoing elective lumbar fixation under general anesthesia. Eligible participants aged 18–65 with ASA physical status I–II will receive one of the analgesic techniques perioperatively and then be followed after surgery. Postoperative pain scores and opioid consumption via patient-controlled analgesia will be recorded, along with standard safety monitoring. Patients with allergies to local anesthetics, recent opioid use, significant comorbidities, or inability to use PCA are excluded.
Why it matters
Potential benefit: If one technique provides better pain relief with less opioid use, patients could experience lower pain levels and fewer opioid-related side effects after lumbar fixation.
How similar studies have gone: Prior small trials and case series have suggested erector spinae plane blocks and local wound infiltration can reduce postoperative pain and opioid use after spine surgeries, but large randomized comparisons are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled to undergo lumbar fixation surgery under general anesthesia * aged between 18 and 65 years, * American Society of Anesthesiologists physical status classification of I-II Exclusion Criteria: * Patients with a known allergy to local anesthetics. * Patients who used opioid analgesics within 48 hours prior to sample collection. * Patients with a history of smoking or alcohol consumption. * Patients with conditions affecting salivary flow, such as xerostomia or those who have undergone radiotherapy. * Patients with infectious diseases known to be transmissible through saliva. * Patients with an ASA physical status classification of III or higher. * Patients unable to use a patient-controlled analgesia (PCA) device. * Patients who do not consent to the study procedures.
Where it's running
-
Ataturk University
Erzurum, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Feyza Simsek — Dr
- Study coordinator: Feyza Simsek
- Email: feyzasimsek0205@gmail.com
- Phone: +90 554 947 52 61
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Premature infants: trying PIOMI with mom to support feeding
Aims to see if PIOMI done with a mother’s presence and voice helps preterm babies feed better and feel more connected to mom.
-
Antibacterial effects of two intracanal medicaments in acute apical abscesses
This randomized trial tests whether calcium hydroxide or a calcium silicate-based medicament more effectively lowers bacterial load in teeth with acute apical abscesses during a 7–10 day medication period.
-
Sevoflurane vs. Propofol for anesthesia in obese adults undergoing lumbar surgery
In adults with obesity undergoing lumbar instrumentation, this study tests whether sevoflurane inhaled anesthesia or propofol IV anesthesia affects inflammatory markers after surgery.
-
Blood enzyme changes and heart risk after bevacizumab eye injections
This tests whether repeated bevacizumab eye injections change blood enzymes linked to cardiovascular risk in people aged 55 and older treated for diabetic retinopathy, retinal vein occlusion, or age-related macular degeneration.
-
Bupivacaine plus lidocaine versus bupivacaine alone for ultrasound-guided popliteal sciatic nerve block
This trial will test whether adding lidocaine to bupivacaine gives faster numbness and longer-lasting pain relief for adults having below-knee (foot or ankle) surgery with an ultrasound-guided popliteal sciatic nerve block.
-
Progressive relaxation with a therapeutic clown to reduce pre-surgery fear and anxiety in children
This trial tests whether progressive relaxation exercises led by a therapeutic clown before circumcision reduce fear, anxiety, and change vital signs in children aged 6–10.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.