Comparing the effects of two orthodontic treatments for jaw growth in children
Comparison of Skeletal Effects of Herbst and Invisalign MA in Growing Patients With KLass Malocclusion
This study is testing which of two orthodontic treatments helps children's jaw growth better in those with a specific bite problem.
Quick facts
| Phase | Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | N/A to 15 Years |
| Sex | All |
| Sponsor | Université Libre de Bruxelles Academic / other |
| Locations | 2 sites (Anderlecht and 1 other locations) |
| Trial ID | NCT06409923 on ClinicalTrials.gov |
What this trial studies
This study compares the skeletal, dental, and soft tissue effects of two orthodontic treatments—Mandibular Advancement aligners and the Herbst appliance—in children with Class II malocclusion. A total of approximately 30 patients aged 9 to 15 years will be recruited from initial orthodontic consultations at ULB's Erasme Hospital. Each patient will receive either treatment, and their progress will be monitored using profile cephalometry and 3D optical scans to minimize unnecessary radiation exposure. The goal is to determine which method is more effective in stimulating mandibular growth.
Who should consider this trial
Good fit: Ideal candidates for this study are children aged 9 to 15 years with Class II skeletal malocclusion and specific cervical vertebral maturation stages.
Not a fit: Patients with advanced cervical vertebral maturation (CVM > 4) or periodontal disease may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective orthodontic treatments for children with Class II malocclusion, potentially improving their dental and skeletal development.
How similar studies have performed: While there have been studies on orthodontic treatments for malocclusion, this specific comparison of Mandibular Advancement aligners and the Herbst appliance is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria * ANB greater than 4°. * Angle Class II molar and canine relationship * cervical vertebral maturation (CVM) CVM2/CVM3 Exclusion Criteria: * CVM\> 4 * periodontal disease
Where this trial is running
Anderlecht and 1 other locations
- Université LIbre de Bruxelles — Anderlecht, Belgium (Recruiting)
- UNiversité Libre de Bruxelles — Brussels, Belgium (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.