Comparing the effects of high-intensity and moderate-intensity exercise on fat loss in young women
Official title: Acute Physiological Responses to Isoenergetic High-Intensity Interval vs. Moderate-Intensity Continuous Exercise in Overweight or Obese Young Females: Focus on Catecholamines, Oxygen Consumption, Lipid Utilization, and Appetite Regulation
Run by Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques · NCT06868862 · Data updated 2026-11-12
This study tests whether high-intensity or moderate-intensity exercise helps young women with overweight or obesity lose more fat and improve their health.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 45 Years |
| Sex | Women only |
| Enrollment | 15 (estimated) |
| Sponsor | Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques Academic / other |
| Locations | 1 site (São Paulo, São Paulo) |
| Status | Recruiting |
| Started | February 1, 2025 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | August 31, 2026 |
| Trial ID | NCT06868862 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are young women aged 18-35 with a BMI between 25-35 kg/m² who are overweight or obese.
✕Probably not a fit
Patients who are menopausal, using contraceptives, or have medical contraindications to intense physical activity may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the acute effects of two types of exercise, High-Intensity Interval Exercise (HIIE) and Moderate-Intensity Continuous Exercise (MICE), on fat mass loss in young women with overweight or obesity. Participants will engage in isoenergetic exercise sessions while key physiological responses, such as plasma catecholamine levels, will be measured to understand the mechanisms behind fat loss. The study aims to clarify which exercise method is more effective for promoting fat loss and improving overall health outcomes.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective exercise strategies for weight management in young women.
How similar studies have gone: Previous studies have shown that high-intensity interval training can be more effective than moderate-intensity continuous training for fat loss, suggesting this approach is promising.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * women with overwieght or obesity (BMI: 25-35 kg/m²) Exclusion Criteria: * contraceptive use * menopause * irregular menstrual cycle * medical contraindications to intense physical activity, * painful joints, * taking ß-blocker
Where it's running
-
Laboratório de Fisiologia e Metabolismo Aplicados à Educação Física
São Paulo, São Paulo, Brazil Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.