Clinical trial Recruiting at 1 site Interventional Ages 20 to 45 Women only

Comparing the effects of high-intensity and moderate-intensity exercise on fat loss in young women

Official title: Acute Physiological Responses to Isoenergetic High-Intensity Interval vs. Moderate-Intensity Continuous Exercise in Overweight or Obese Young Females: Focus on Catecholamines, Oxygen Consumption, Lipid Utilization, and Appetite Regulation

Run by Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques · NCT06868862 · Data updated 2026-11-12

This study tests whether high-intensity or moderate-intensity exercise helps young women with overweight or obesity lose more fat and improve their health.

More Overweight and Obese Adults trials

Quick facts

Study typeInterventional
Ages20 Years to 45 Years
SexWomen only
Enrollment15 (estimated)
SponsorLaboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Academic / other
Locations1 site (São Paulo, São Paulo)
StatusRecruiting
StartedFebruary 1, 2025
Main results expectedDecember 30, 2026
Study endsDecember 30, 2026
Registry record updatedAugust 31, 2026
Trial IDNCT06868862 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are young women aged 18-35 with a BMI between 25-35 kg/m² who are overweight or obese.

Probably not a fit

Patients who are menopausal, using contraceptives, or have medical contraindications to intense physical activity may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the acute effects of two types of exercise, High-Intensity Interval Exercise (HIIE) and Moderate-Intensity Continuous Exercise (MICE), on fat mass loss in young women with overweight or obesity. Participants will engage in isoenergetic exercise sessions while key physiological responses, such as plasma catecholamine levels, will be measured to understand the mechanisms behind fat loss. The study aims to clarify which exercise method is more effective for promoting fat loss and improving overall health outcomes.

Why it matters

Potential benefit: If successful, this study could provide insights into more effective exercise strategies for weight management in young women.

How similar studies have gone: Previous studies have shown that high-intensity interval training can be more effective than moderate-intensity continuous training for fat loss, suggesting this approach is promising.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* women with overwieght or obesity (BMI: 25-35 kg/m²)

Exclusion Criteria:

* contraceptive use
* menopause
* irregular menstrual cycle
* medical contraindications to intense physical activity,
* painful joints,
* taking ß-blocker

Where it's running

  • Laboratório de Fisiologia e Metabolismo Aplicados à Educação Física
    São Paulo, São Paulo, Brazil
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.