Comparing the effects of high-intensity and moderate-intensity exercise on fat loss in young women

Acute Physiological Responses to Isoenergetic High-Intensity Interval Vs. Moderate-Intensity Continuous Exercise in Overweight or Obese Young Females: Focus on Catecholamines, Oxygen Consumption, Lipid Utilization, and Appetite Regulation

Not applicable Interventional Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques · NCT06868862

This study tests whether high-intensity or moderate-intensity exercise helps young women with overweight or obesity lose more fat and improve their health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages20 Years to 45 Years
SexFemale
SponsorLaboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques Academic / other
Locations1 site (São Paulo, São Paulo)
Trial IDNCT06868862 on ClinicalTrials.gov

What this trial studies

This study investigates the acute effects of two types of exercise, High-Intensity Interval Exercise (HIIE) and Moderate-Intensity Continuous Exercise (MICE), on fat mass loss in young women with overweight or obesity. Participants will engage in isoenergetic exercise sessions while key physiological responses, such as plasma catecholamine levels, will be measured to understand the mechanisms behind fat loss. The study aims to clarify which exercise method is more effective for promoting fat loss and improving overall health outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are young women aged 18-35 with a BMI between 25-35 kg/m² who are overweight or obese.

Not a fit: Patients who are menopausal, using contraceptives, or have medical contraindications to intense physical activity may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into more effective exercise strategies for weight management in young women.

How similar studies have performed: Previous studies have shown that high-intensity interval training can be more effective than moderate-intensity continuous training for fat loss, suggesting this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* women with overwieght or obesity (BMI: 25-35 kg/m²)

Exclusion Criteria:

* contraceptive use
* menopause
* irregular menstrual cycle
* medical contraindications to intense physical activity,
* painful joints,
* taking ß-blocker

Where this trial is running

São Paulo, São Paulo

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Overweight and Obese AdultsHigh Intensity Interval Exerciseoxygen consumptionhigh intensity interval trainingsubstrate oxydationcatecholaminesobesity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.