Comparing the carbon footprint of endoscopic ultrasound versus MRCP for suspected common bile duct stones

Prospective Comparison of the Carbon Footprint of Endoscopic Ultrasound (EUS) vs Magnetic Resonance Cholangiopancreatography (MRCP) for Evaluation of Suspected Choledocholithiasis

Observational Asian Institute of Gastroenterology, India · NCT07283185

This project will test whether endoscopic ultrasound (EUS) produces a smaller carbon footprint than MRCP when used to check for common bile duct (CBD) stones in adults with intermediate risk.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorAsian Institute of Gastroenterology, India Academic / other
Locations1 site (Hyderabad, Telangana)
Trial IDNCT07283185 on ClinicalTrials.gov

What this trial studies

This observational study will measure and compare greenhouse gas emissions (CO2e) associated with diagnostic MRCP and EUS performed for adults with intermediate likelihood of CBD stones at a single tertiary center. Participants are adults referred for either MRCP or EUS per standard clinical care, and the trial will capture energy use, equipment and facility contributions, and downstream procedure needs such as same-session ERCP. The design builds on prior randomized data showing similar diagnostic performance between the two tests and prior work suggesting lower emissions from EUS. Results will be reported as per-procedure carbon footprints to inform more sustainable diagnostic choices.

Who should consider this trial

Good fit: Adults (age ≥18) with an intermediate likelihood of CBD stone per ESGE guidelines who are undergoing either MRCP or EUS are the ideal candidates.

Not a fit: Patients categorized as high or low likelihood for CBD stone, those with contraindications to either modality, or those undergoing both tests simultaneously would not be expected to benefit from this comparison.

Why it matters

Potential benefit: If successful, the findings could help clinicians choose a lower-carbon diagnostic option and reduce the environmental impact of care without compromising diagnosis.

How similar studies have performed: A landmark randomized trial has shown MRCP and EUS are diagnostically equivalent for intermediate-risk patients, and prior research has shown diagnostic EUS often produces substantially less CO2e per procedure than radiologic imaging.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥18 years
* Intermediate likelihood of CBD stone (per ESGE)
* Undergoing either MRCP or EUS for evaluation

Exclusion Criteria:

* High or low likelihood category (per ESGE)
* Undergoing both MRCP and EUS simultaneously
* Contraindications to either modality

Where this trial is running

Hyderabad, Telangana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Choledocholithiasis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.