Comparing tests for diagnosing asthma
A Comparison of Diagnostic Testing Modalities in the Assessment of Asthma
Portsmouth Hospitals NHS Trust · NCT06286085
This study is testing how well a new non-invasive lung test called impulse oscillometry works for diagnosing asthma compared to traditional methods for patients at a severe asthma clinic.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Portsmouth Hospitals NHS Trust (other gov) |
| Locations | 1 site (Portsmouth) |
| Trial ID | NCT06286085 on ClinicalTrials.gov |
What this trial studies
This observational study evaluates the effectiveness of various diagnostic approaches for asthma, focusing on the concordance of international guidelines and the use of impulse oscillometry (IOS) as a non-invasive lung function test. By analyzing data from patients attending the severe asthma service at Queen Alexandra Hospital in Portsmouth, the study aims to identify how well IOS performs compared to traditional diagnostic criteria. The research will utilize an 'opt-out' consent process to assess routine outpatient lung function data, contributing valuable insights into asthma diagnosis. The goal is to enhance the accuracy and ease of diagnosing asthma, addressing inconsistencies in current practices.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and over who have undergone full asthma workups and are referred for asthma diagnosis and management.
Not a fit: Patients with primary respiratory conditions other than asthma, such as interstitial lung disease (ILD), may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate and consistent asthma diagnoses, improving patient management and outcomes.
How similar studies have performed: While the use of impulse oscillometry in asthma diagnosis is promising, current research on its effectiveness is limited, making this study a novel exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The patient will meet all the following criteria to be considered eligible for the study: * Aged 18 years or over. * All patients who have attended full asthma workups from November 2021 till date * Willing and able to consent to use their data in this study (opt-out form or e-consent). * Patients referred to the Portsmouth asthma service for diagnosis and further management of presumed asthma. Comorbidities are common in asthma, thus patients with co-existing conditions such as obesity, bronchiectasis or COPD will be included. Exclusion Criteria: * The participant may not enter the study if either of the following apply: * Unable to comprehend the study and provide informed consent, e.g., insufficient command of English in the absence of someone who can adequately interpret. * Patients with other primary respiratory conditions, such as ILD.
Where this trial is running
Portsmouth
- Portsmouth Hospitals University NHS Trust — Portsmouth, United Kingdom (RECRUITING)
Study contacts
- Principal investigator: Anoop Chauhan — Portsmouth University Hospital Trust
- Study coordinator: celia Selvin-Premkumar
- Email: celia.selvin-premkumar@porthosp.nhs.uk
- Phone: 02392 286000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Asthma, lung function, impulse oscillometry