Comparing telephone support to self-guidance in an online program for depression

Telephone Support vs. Self-guidance in an Internet-based Self-administered Psychological Program for the Treatment of Depression

NA · Universitat Jaume I · NCT06230237

This study is testing whether getting professional phone support while using an online therapy program for depression helps people more than just going through the program on their own.

Quick facts

PhaseNA
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversitat Jaume I (other)
Locations1 site (Tavernes de la Valldigna, Valencia)
Trial IDNCT06230237 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effectiveness of an internet-based cognitive behavioral therapy program called 'Smiling is Fun' for individuals with depression in a primary care setting. It will compare the outcomes of participants receiving professional telephone support against those who will self-guide through the program. The research will focus on adherence rates and the implementation process of the program, addressing barriers to accessing mental health care. By utilizing a randomized controlled trial design, the study seeks to provide insights into how to improve access to psychological interventions.

Who should consider this trial

Good fit: Ideal candidates are Spanish-speaking adults aged 18 to 65 who meet the diagnostic criteria for major depressive disorder and have mild to moderate symptoms.

Not a fit: Patients with severe depression or those who do not have internet access may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance access to effective psychological treatments for depression, particularly in primary care settings.

How similar studies have performed: Previous studies have shown success with similar internet-based cognitive behavioral therapy approaches, indicating potential for this method.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 to 65 years.
* Ability to understand and read Spanish.
* Meet diagnostic criteria for major depressive disorder (DSM-5).
* Mild or moderate symptoms of the Spanish version of the Beck Depression Inventory-II (BDI-II) (14-19: mild depression; 20-28: moderate depression).
* Episode duration of more than two weeks.
* Have internet access at home and an email account.
* The diagnosis of major depressive disorder will be confirmed by the standardized MINI International Neuropsychiatric Interview.

Where this trial is running

Tavernes de la Valldigna, Valencia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Depression, Internet Based Intervention, Psychological Intervention, Professional Support, Mental Health, Self-guided

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.