Comparing techniques for relieving small bowel obstruction
Multicenter Non-randomized Controlled Retrospective Study of the Small Bowel Decompression Techniques Comparative Effectiveness in Patients With Benign Small Bowel Obstruction
This study is testing different methods to relieve small bowel obstruction in patients to see which technique works best during and after surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | North-Western State Medical University named after I.I.Mechnikov Academic / other |
| Locations | 8 sites (Chelyabinsk and 7 other locations) |
| Trial ID | NCT06175442 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the effectiveness of various intestinal decompression techniques in patients suffering from small bowel obstruction. It will analyze outcomes based on a comparison group using nasogastric drainage against three main groups employing more active decompression methods, such as drainage of the initial parts of the small intestine or total intubation. The study will focus on patients with acute adhesive intestinal obstruction, incarcerated hernias, and other related conditions. The goal is to determine which method yields better results in relieving obstruction during and after surgery.
Who should consider this trial
Good fit: Ideal candidates include patients with acute adhesive intestinal obstruction, incarcerated ventral hernias, or obstruction due to foreign bodies.
Not a fit: Patients with peritonitis, those requiring intestinal resection, or those who have undergone laparostomy may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for patients with small bowel obstruction, enhancing recovery and outcomes.
How similar studies have performed: While there have been studies on intestinal decompression, this specific comparative approach is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * acute adhesive intestinal obstruction, including strangulation forms; * incarcerated ventral hernias, accompanied by impaired intestinal passage; * acute adhesive intestinal obstruction in the hernial sac; * obstruction of the small intestine lumen with gallstones and other foreign bodies. Exclusion Criteria: * with peritonitis and other complicated surgical infection; * operations with intestinal resection; * patients after laparostomy
Where this trial is running
Chelyabinsk and 7 other locations
- Chelyabinsk regional clinical hospital — Chelyabinsk, Russian Federation (Recruiting)
- City Clinical Hospital No. 40 — Ekaterinburg, Russian Federation (Recruiting)
- City Clinical Hospital №4 — Perm, Russian Federation (Recruiting)
- North-Western State Medical University named after I. I. Mechnikov — Saint Petersburg, Russian Federation (Recruiting)
- Saint-Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine — Saint Petersburg, Russian Federation (Recruiting)
- St Petersburg State Budgetary Institution Of Health Care City Mariinskaya Hospital — Saint Petersburg, Russian Federation (Recruiting)
- The City Hospital of the Holy Martyr Elizabeth — Saint Petersburg, Russian Federation (Recruiting)
- State Healthcare Facility "City Clinical Emergency Hospital No 25" — Volgograd, Russian Federation (Recruiting)
Study contacts
- Study coordinator: Pavel A Kotkov, PhD
- Email: kotkovdr@mail.ru
- Phone: +79062619231
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.