Comparing techniques for pediatric kidney transplantation
The Optimal Method for Ureter Implantation in Pediatric Kidney Transplantation
This study looks at two different ways to connect a new kidney to the bladder in kids who have had a kidney transplant to see which method leads to fewer urinary problems.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 398 (estimated) |
| Ages | 0 Years to 18 Years |
| Sex | All |
| Sponsor | Radboud University Medical Center Academic / other |
| Locations | 1 site (Nijmegen) |
| Trial ID | NCT05397821 on ClinicalTrials.gov |
What this trial studies
This observational study aims to retrospectively compare two techniques of ureteroneocystostomy (UNC) in pediatric kidney transplant recipients. Researchers will analyze data from patients who received kidney grafts between 1994 and 2018 at Radboud University Medical Center and UW Health University Hospital. Additionally, urologists at these centers will complete a survey regarding their preferences for UNC techniques and suture materials used. The focus is on assessing the impact of these techniques on urinary tract infections and ureteral obstruction.
Who should consider this trial
Good fit: Ideal candidates are pediatric patients under 19 who received a kidney graft at the participating centers between 1994 and 2018.
Not a fit: Patients who had a loss of follow-up data of less than one year will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical techniques that reduce complications in pediatric kidney transplant patients.
How similar studies have performed: While this study focuses on a specific comparison of techniques, similar studies have shown that optimizing surgical methods can significantly reduce complications in kidney transplantation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * received kidney graft in the participating centres at an age \<19 * received kidney graft between 1994-2018 * follow-up data of at least 1 year Exclusion Criteria: - Loss of follow up \< 1 year
Where this trial is running
Nijmegen
- Radboud University Medical Center — Nijmegen, Netherlands (Recruiting)
Study contacts
- Principal investigator: Liesbeth Lamers, MD — Radboud University Medical Center
- Study coordinator: Loes Oomen, MD
- Email: loes.oomen@radboudumc.nl
- Phone: +31613971379
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.