Comparing techniques for locating non-palpable breast lesions before surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates different localization techniques for non-palpable breast lesions in patients undergoing breast conservative surgery. It focuses on comparing the effectiveness of wire guided localization, radioactive seed localization, and carbon dye methods to ensure accurate detection and complete resection of tumors. The study aims to identify the best approach to minimize the risk of local recurrence and the need for additional surgeries. By analyzing data from multiple centers, it seeks to provide insights into the most effective preoperative strategies for these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female sex;
* Patients who underwent breast conservative surgery for non-palpable occult breast lesions;
* Intraoperative localization of breast lesion with WGL, ROLL, magnetic seed, carbon dye;
* Preoperative diagnosis on histology or cytology of borderline lesion (B3 or C3) or malignant lesion (B4-B5 or C4-C5).

Exclusion Criteria:

* Diagnosis of benign breast lesion, both on preoperative needle breast biopsy (B2) or on fine needle breast aspiration (C2);
* Clinically palpable breast lesion;
* Localization of a non-palpable lesion through two or more different techniques;
* Breast tumor localization with clip in patients who underwent neoadjuvant chemotherapy.

Where it's running

• Istituti Clinici Scientifici Maugeri SpA
  Pavia, Lombardia, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.