Comparing techniques for carotid artery surgery
Conventional Vs. Eversion Carotid Endarterectomy Immediate and Short-Term Outcomes
NA · Sohag University · NCT06207643
This study is testing which of two surgical methods for carotid artery surgery works better and is safer for patients with narrowed arteries who have had brain-related issues.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06207643 on ClinicalTrials.gov |
What this trial studies
This interventional study aims to compare the safety and effectiveness of two techniques for carotid endarterectomy: conventional carotid endarterectomy (C-CEA) and eversion carotid endarterectomy (E-CEA). Participants with carotid artery stenosis will undergo one of the two surgical techniques, and the outcomes will be evaluated to determine which method yields better results. The study focuses on patients who have experienced cerebral events or have significant carotid artery stenosis. By analyzing postoperative results, the researchers hope to clarify the advantages of each technique.
Who should consider this trial
Good fit: Ideal candidates include patients with carotid artery stenosis who have experienced recent strokes or have high-grade stenosis with increasing symptoms.
Not a fit: Patients with non-atherosclerotic carotid artery stenosis or those who have had recent acute ischemic strokes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and reduced stroke risk for patients undergoing carotid artery surgery.
How similar studies have performed: Previous studies have shown mixed results regarding the effectiveness of C-CEA and E-CEA, indicating that this comparison is relevant and necessary.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients having carotid artery stenosis with cerebral events (recent stroke). * Patients having high grade carotid artery stenosis with increasing symptoms. * Patients underwent previously CEA presented with carotid restenosis. Exclusion Criteria: * Non atherosclerotic carotid artery stenosis e.g., vasculitis, collagen vascular diseases and hypoplastic ICA. * patients with recently thrombosed ICA. * High carotid bifurcation to the extent makes CEA not accessible in easy or safe way e.g., increased risk of cranial nerve injury. * acute ischemic stroke within less than 2 weeks before the procedure.
Where this trial is running
Sohag
- Sohag University — Sohag, Egypt (RECRUITING)
Study contacts
- Principal investigator: kariem Mohamed — sohag faculty of medicine
- Study coordinator: kariem Ay Mohamed
- Email: kareem.mahmoud@med.sohag.edu.eg
- Phone: +201010455201
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Carotid Stenosis, Carotid Atherosclerosis, Carotid Artery Plaque, carotid endarterectomy