Comparing suture mesh and planar mesh for small ventral hernia repair
Official title: Mesh Matters: Evaluating the Efficacy of Suture Mesh vs. Planar Mesh in Ventral Hernia Treatment - a Randomized, Blinded Multicenter Study
Run by Regionshospital Nordjylland · NCT07476560 · Data updated 2026-11-12
This trial will test whether using mesh-suture instead of planar mesh during repair of small ventral hernias in adults leads to fewer wound problems, better quality of life, and shorter operation times.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 280 (estimated) |
| Sponsor | Regionshospital Nordjylland Government |
| Locations | 1 site (Hjørring) |
| Status | Recruiting |
| Started | January 5, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2032 |
| Registry record updated | March 17, 2026 |
| Trial ID | NCT07476560 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults eligible for elective repair of a ventral hernia up to 3 × 3 cm on ultrasound or CT who can undergo either mesh-suture or planar mesh repair and attend follow-up visits.
✕Probably not a fit
Patients requiring emergency (acute) surgery, pregnant women or those planning future pregnancy, and anyone under 18 are excluded and would not be expected to benefit from this trial.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adult patients with small ventral hernias (maximum 3 × 3 cm on imaging) are randomized to repair with either mesh-suture or standard planar mesh. Baseline clinical data and quality-of-life (QoL) scores are collected before surgery, and patients return for a wound inspection and ultrasound on postoperative day 7–13. QoL is re-measured at 90 days and operation time and wound complication rates are recorded as key outcomes. Results will directly compare complication rates, patient-reported QoL, and operative duration between the two implant approaches.
Why it matters
Potential benefit: If successful, mesh-suture could reduce postoperative wound complications and improve recovery and quality of life after small ventral hernia repair.
How similar studies have gone: Similar device and mesh-design approaches have shown promising but mixed results in small studies, and large randomized evidence comparing mesh-suture to planar mesh is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ventral hernia (maximum size 3 × 3 cm) measured with Ultrasound or CT. * Participants must be eligible for surgical repair using either mesh-suture or planar mesh Exclusion Criteria: * Age \< 18 years. * Acute (emergent) operation. * Pregnancy. * Women with plans for future pregnancies. * Withdrawal of informed consent during admission.
Where it's running
-
Regionshospital Nordjylland
Hjørring, Denmark Recruiting
Study contacts
- Study coordinator: Vitaly A Gameza
- Email: vitgam@rn.dk
- Phone: 045 97640520
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Robotic Single-Port Repair of Concomitant Inguinal and Umbilical Hernias
Doctors are testing a new robotic single-port technique to fix both an inguinal hernia and an umbilical hernia at the same time in adults.
-
Weight loss before surgery for abdominal wall hernia repair
This study is testing if a weight loss program before surgery can help people with obesity have better results after abdominal wall hernia repair compared to those who have surgery right away.
-
International registry for emergency surgery and trauma
This study is setting up a worldwide registry for emergency surgeries and trauma cases to help doctors track their results and find better ways to treat patients.
-
Transplanting abdominal wall tissue to repair defects
This study is testing if transplanting abdominal wall tissue can safely fix defects in the abdominal area for people who need it.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.