Comparing survival rates in endometrial cancer patients after laparoscopic hysterectomy with and without a uterine manipulator

Comparison of Five-year Survival and Disease-free Survival in Patients Diagnosed With Endometrium Cancer Who Underwent Total Laparoscopic Hysterectomy With and Without Uterine Manipulator

Observational Gaziosmanpasa Research and Education Hospital · NCT06307886

This study looks at whether using a uterine manipulator during laparoscopic surgery for endometrial cancer helps patients live longer and stay cancer-free compared to those who don’t use it.

Quick facts

Study typeObservational
Enrollment108 (estimated)
Ages18 Years to 75 Years
SexFemale
SponsorGaziosmanpasa Research and Education Hospital Government
Locations1 site (Istanbul)
Trial IDNCT06307886 on ClinicalTrials.gov

What this trial studies

This study compares the five-year survival and disease-free survival rates of patients diagnosed with endometrial cancer who underwent total laparoscopic hysterectomy, with some patients using a uterine manipulator and others not. It aims to determine if the use of a uterine manipulator during surgery affects long-term outcomes. The study is observational and will analyze data from patients aged 18 to 75 diagnosed with FIGO stage 1 and 2 endometrial cancer. The findings could provide insights into surgical techniques and their impact on patient prognosis.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 18 to 75 diagnosed with FIGO stage 1 and 2 endometrial cancer who are suitable for laparoscopic surgery.

Not a fit: Patients diagnosed with FIGO stage 3 and 4 endometrial cancer or those not suitable for laparoscopic surgery will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could help refine surgical approaches for endometrial cancer, potentially improving patient survival and quality of life.

How similar studies have performed: While this study's specific approach is not widely tested, similar studies have shown varying outcomes regarding surgical techniques in cancer treatment.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients suitable for laparoscopic surgery patients ages 18-75 patients diagnosed figo stage 1 and 2 endometrial cancer

Exclusion Criteria:

* patients not suitable for laparoscopic surgery patients diagnosed figo stage 3 and 4 endometrial cancer pregnant patients

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Endometrial Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.