Comparing surgical approaches and artery embolization for acute subdural hematoma
Acute Subdural Hematoma Registry
This project will collect past patient data to see if different surgeries and middle meningeal artery embolization affect survival for adults with acute subdural hematoma.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Methodist Health System Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT07490197 on ClinicalTrials.gov |
What this trial studies
This retrospective project will build a data repository from the Methodist Dallas Medical Center trauma registry including adults with acute subdural hematoma identified within 72 hours of injury. The repository will capture standard surgical treatments such as burr hole trephination, craniotomy, decompressive craniectomy, and middle meningeal artery embolization, plus clinical and outcome data. Analyses will focus on survival outcomes and enable quality-improvement observations comparing those interventions. Patients under 18, prisoners, and pregnant persons are excluded from the dataset.
Who should consider this trial
Good fit: Adults (age ≥18) treated at Methodist Dallas Medical Center with an acute subdural hematoma identified on CT or MRI within 72 hours and included in the hospital trauma registry.
Not a fit: Children, pregnant persons, prisoners, and patients treated outside the registry or presenting more than 72 hours after injury are not represented and may not benefit from these findings.
Why it matters
Potential benefit: If successful, the work could clarify which interventions, including middle meningeal artery embolization, are associated with better survival and help guide treatment decisions.
How similar studies have performed: Middle meningeal artery embolization has shown promising results in observational work for chronic subdural hematoma, but its role in acute subdural hematoma remains less established and largely supported by limited retrospective reports.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ≥18 years old * Included in the Methodist Dallas Medical Center Trauma Registry * Acute subdural hematoma identified on computed tomography scan or magnetic resonance imaging of the brain in the trauma bay within 72 hours of a traumatic event Exclusion Criteria: * \<18 years old * Prisoners, pregnant persons, or other protected population
Where this trial is running
Dallas, Texas
- Methodist Dallas Medical Center- Clinical Research Institute — Dallas, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Andrew Karpisek, MD — Methodist Health System
- Study coordinator: Crystee Cooper, DHEd
- Email: ClinicalResearch@mhd.com
- Phone: 214-947-1280
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.