Comparing surgery and medical management for long-term diabetes remission

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the long-term effects of three types of bariatric surgeries—Roux-en-Y Gastric Bypass, Sleeve Gastrectomy, and Biliopancreatic Diversion with Duodenal Switch—on patients with type 2 diabetes. It aims to measure metabolic, renal, and cardiovascular outcomes, hypothesizing that these surgeries may have unrecognized benefits for diabetic patients. The study will involve a longitudinal approach to assess the impact of these surgical interventions compared to best medical management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* BMI ≥ 35
* type 2 diabetes
* HbA1c ≥ 6,5 % or fasting glycemia ≥7mmol/l or non-fasting glycemia ≥11mmol/l
* able to consent

Exclusion Criteria:

* pregnancy
* past esophageal, gastric or bariatric surgery
* irritable bowel, unexplained intermittent vomiting, severe abdominal pain, chronic diarrhea or constipation
* history of gastric or duodenal ulcers
* pre-operatory hypoalbuminemy
* history of renal, hepatic, cardiac or pulmonary severe disease
* taken of corticosteroid in the last month
* evidence of psycological problem that may affect the capacity to understand the project and to comply with the medical recommandations
* history of drug use or alcool abuse in the last 12 months
* history of gastro-intestinal inflammatory diseases

Where it's running

• Institut Universitaire de Cardiologie et de Pneumologie de Québec
  Québec, Quebec, Canada Recruiting

Study contacts

• Study coordinator: Melanie Nadeau, MSc
• Email: melanie.nadeau@criucpq.ulaval.ca
• Phone: 418-656-8711

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.