Comparing stress response and intubation time with video versus direct laryngoscopes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-blind, randomized comparison of video laryngoscopy (VL) versus direct laryngoscopy (DL) in adults undergoing elective surgery that requires endotracheal intubation. Participants (ASA I–II, age 18–60, BMI <30, Mallampati I–II) are randomly assigned to VL or DL and receive the same anesthesia protocol with standard monitoring (NIBP, ECG, SpO2). Hemodynamic measurements are recorded before induction, at one and three minutes after induction/ventilation, and at one, three, and five minutes after intubation, and the time required to intubate is recorded. The trial is conducted at the Sindh Institute of Urology and Transplantation in Karachi, Pakistan.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA I \& II
* Age 18-60 years.
* Preoperatively nonhypertensive and hemodynamically stable patients
* Patients scheduled for elective procedures not involving airway surgeries
* Patients with informed consent
* Mallampati score I and II
* Interincisor gap \> 3 cms
* BMI less than 30 kg/m²

Exclusion Criteria

* Patient refusal
* ASA III, IV \& V
* Hemodynamically unstable patients
* Patients with Hypertension and Ischemic Heart Disease (whether controlled or uncontrolled)
* Airway abnormalities, including congenital airway malformations \& maxillofacial abnormalities
* Head, neck or any facial traumas or history of prior head, neck or airway surgeries
* Emergency procedures
* Pregnancy

Where it's running

• Sindh Institute of Urology and Transplantation
  Karachi, Sindh, Pakistan Recruiting

Study contacts

• Principal investigator: Syed M Abbas — Sindh Institute of Urology and Transplantation
• Study coordinator: Syed M Abbas, FCPS
• Email: smabbas1969@gmail.com
• Phone: 02199215718

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Timing of a single dexmedetomidine dose before laryngoscopy and intubation and its effect on stress response.

  This trial will test whether giving one dose of dexmedetomidine earlier or closer to surgery can reduce the blood pressure and heart rate changes caused by laryngoscopy and intubation in adults aged 18–65 with ASA I–II.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07165483

• How neck measurements relate to airway checks to help in intubation

  This observational study tests whether the thyromental distance or the mandibular triangle length best predicts the distance to the incisor vallecula to aid choosing the right laryngoscope blade for intubation.

  Recruiting Sir Ganga Ram Hospital · New Delhi, National Capital Territory of Delhi · NCT07668297

• Daily cranberry juice to boost stress resilience during multitasking

  This will test whether 70 days of daily cranberry juice helps healthy adults aged 30–55 stay calmer and perform better on thinking and motor tasks when multitasking.

  Recruiting University of Florida · Gainesville, Florida · NCT07453537

• Nalbuphine versus fentanyl to reduce blood pressure and heart rate changes during laryngoscopy and intubation

  This test sees if nalbuphine or fentanyl better prevents spikes in heart rate and blood pressure during intubation for people having cardiac surgery.

  Recruiting Phase 4 Rawalpindi Institute of Cardiology · Rawalpindi, Punjab Province · NCT07435337

• Stress patterns and anhedonia during adolescence

  We will see if combining brain scans, stress hormones, and heart-rate measures can identify patterns linked to developing anhedonia in 13–15-year-olds.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07040449

• Improving predictions for difficult airway management

  This study is testing a new scoring system that uses both traditional checks and ultrasound images to better predict if adults will have a hard time with their airway during anesthesia.

  Recruiting American University of Beirut Medical Center · Beirut · NCT06815952

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.