Comparing Stellate Ganglion Block and Oral Medications for Sweaty Palms

The Efficacy of Stellate Ganglion Block Versus Combined Oral Anticholinergic and Antidepressant Drugs on Treatment of Palmar Hyperhidrosis; A Randomized Comparative Study

Not applicable Interventional Fayoum University · NCT06731101

This study is trying to see if a nerve block or a mix of oral medications works better for people aged 20 to 45 with sweaty palms.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages20 Years to 45 Years
SexAll
SponsorFayoum University Academic / other
Locations1 site (Fayoum)
Trial IDNCT06731101 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effectiveness of a stellate ganglion block against a combination of oral anticholinergic and antidepressant medications in treating palmar hyperhidrosis, a condition characterized by excessive sweating of the palms. Participants aged 20 to 45 with primary palmar hyperhidrosis will be enrolled, and their responses to the two treatment approaches will be evaluated. The study seeks to determine which method provides better relief from symptoms and improves quality of life for affected individuals.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals aged 20 to 45 who experience primary palmar hyperhidrosis.

Not a fit: Patients who are unable to cooperate or have known allergies to anticholinergic or antidepressant drugs may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more effective treatment option for patients suffering from palmar hyperhidrosis.

How similar studies have performed: While there have been studies on treatments for hyperhidrosis, the specific comparison of stellate ganglion block versus oral medications in this context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria: -

1. Age from 20 to 45 years.
2. Both genders.
3. Exhibiting primary palmar hyperhidrosis. Exclusion criteria: -

1. An inability of patient to cooperate. 2. Known allergies to anticholinergic or antidepressant drugs.

Where this trial is running

Fayoum

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Palmar HyperhidrosisStellate ganglion block
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.