Comparing standard physiotherapy and eccentric exercises for de Quervain's disease treatment
De Quervain's Disease in the Acute Phase: Randomized Interventional Study Aimed at Evaluating the Effectiveness of Standard Physiotherapy Treatment (HANDGUIDE), Compared to Experimental Treatment After Performing Ultrasound-guided Infiltrative Therapy.
This study tests whether standard physiotherapy or a special exercise program can help people with de Quervain's disease feel less pain and improve their daily activities.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 134 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Istituto Ortopedico Rizzoli Academic / other |
| Locations | 1 site (Bologna) |
| Trial ID | NCT06296472 on ClinicalTrials.gov |
What this trial studies
This study aims to evaluate the effectiveness of standard physiotherapy treatment against an experimental treatment involving eccentric exercises for patients with de Quervain's disease. Participants will be divided into two groups: one receiving standard treatment based on European guidelines after ultrasound-guided corticosteroid infiltration, and the other engaging in a program of eccentric exercises. The primary focus is on measuring pain reduction and disability improvement in both groups. The study will include patients diagnosed with de Quervain syndrome confirmed through clinical examination and ultrasound.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a medical diagnosis of de Quervain syndrome.
Not a fit: Patients with other hand pathologies or those who are not self-sufficient may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective treatment option for patients suffering from de Quervain's disease.
How similar studies have performed: While there have been studies on treatment for de Quervain's disease, the specific comparison of standard physiotherapy and eccentric exercises is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of both sexes with a minimum age of 18 years; * Medical diagnosis of de Quervain syndrome assessed through orthopedic clinical examination e confirmation by ultrasound; * Signing of the informed consent and participation in the study. Exclusion Criteria: * Patients who are not self-sufficient or not able to understand and want; * Presence of other pathologies in the hand affected by de Quervain pathology, such as intersection syndrome, neuropathies, fractures, rhizoarthrosis, arthrosis of the radio-carpal or intercarpal joint, intercarpal instability, cervical radiculopathy, rheumatic or metabolic pathologies; * Pregnant or breastfeeding women.
Where this trial is running
Bologna
- Istituto Ortopedico Rizzoli — Bologna, Italy (Recruiting)
Study contacts
- Study coordinator: Federico Pilla, MD
- Email: federico.pilla@ior.it
- Phone: 0516366
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.