Clinical trial Recruiting at 3 sites Interventional Ages 40 and up

Comparing standard and 3D colonoscopy for detecting adenomas in patients with positive fecal tests

Official title: Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test Group: A Multi-center, Randomized Controlled Trial

Run by National Taiwan University Hospital · NCT06678477 · Data updated 2026-11-12

This study is testing whether a new 3D colonoscopy method can find more adenomas in patients who have positive fecal tests compared to the standard colonoscopy.

Quick facts

Study typeInterventional
Ages40 Years and up
SexAll
Enrollment298 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations3 sites (Hsinchu and 2 other locations)
StatusRecruiting
StartedJanuary 1, 2024
Main results expectedDecember 31, 2026
Study endsFebruary 28, 2027
Registry record updatedSeptember 29, 2026
Trial IDNCT06678477 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 40 and older who have received a positive result from a fecal immunochemical test.

Probably not a fit

Patients with contraindications for colonoscopy, a history of colectomy, or inflammatory bowel disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares the effectiveness of conventional colonoscopy with a 3D colonoscopy technique in detecting adenomas in patients who have tested positive on a fecal immunochemical test. The focus is on improving the adenoma detection rate (ADR), which is crucial for preventing colorectal cancer. The study aims to determine if the 3D technology can enhance the detection of non-polypoid lesions that are often missed during standard procedures. Participants will undergo colonoscopy using both methods to evaluate performance differences.

Why it matters

Potential benefit: If successful, this study could lead to improved detection rates of pre-cancerous lesions, thereby reducing the incidence of colorectal cancer.

How similar studies have gone: Previous studies have indicated that advanced colonoscopy techniques can improve adenoma detection rates, suggesting potential success for this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Subjects who are 40 years of older
* Subjects who have positive fecal immunochemical test

Exclusion Criteria:

* Contraindication for colonoscopy
* Subjects with familiar or hereditary polyposis
* Subjects with history of colectomy
* Inadequate bowel cleansing level
* Subjects with inflammatory bowel disease

Where it's running

  • National Taiwan University Hospital, Hsinchu Branch
    Hsinchu, Taiwan
    Recruiting
  • National Taiwan University Cancer Center
    Taipei, Taiwan
    Recruiting
  • National Taiwan University Hospital
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.