Comparing standard and 3D colonoscopy for detecting adenomas in patients with positive fecal tests
Official title: Comparison of the Performance Between Conventional Colonoscopy and 3D Colonoscopy in Positive Fecal Immunochemical Test Group: A Multi-center, Randomized Controlled Trial
Run by National Taiwan University Hospital · NCT06678477 · Data updated 2026-11-12
This study is testing whether a new 3D colonoscopy method can find more adenomas in patients who have positive fecal tests compared to the standard colonoscopy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years and up |
| Sex | All |
| Enrollment | 298 (estimated) |
| Sponsor | National Taiwan University Hospital Academic / other |
| Locations | 3 sites (Hsinchu and 2 other locations) |
| Status | Recruiting |
| Started | January 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | February 28, 2027 |
| Registry record updated | September 29, 2026 |
| Trial ID | NCT06678477 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 40 and older who have received a positive result from a fecal immunochemical test.
✕Probably not a fit
Patients with contraindications for colonoscopy, a history of colectomy, or inflammatory bowel disease may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study compares the effectiveness of conventional colonoscopy with a 3D colonoscopy technique in detecting adenomas in patients who have tested positive on a fecal immunochemical test. The focus is on improving the adenoma detection rate (ADR), which is crucial for preventing colorectal cancer. The study aims to determine if the 3D technology can enhance the detection of non-polypoid lesions that are often missed during standard procedures. Participants will undergo colonoscopy using both methods to evaluate performance differences.
Why it matters
Potential benefit: If successful, this study could lead to improved detection rates of pre-cancerous lesions, thereby reducing the incidence of colorectal cancer.
How similar studies have gone: Previous studies have indicated that advanced colonoscopy techniques can improve adenoma detection rates, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Subjects who are 40 years of older * Subjects who have positive fecal immunochemical test Exclusion Criteria: * Contraindication for colonoscopy * Subjects with familiar or hereditary polyposis * Subjects with history of colectomy * Inadequate bowel cleansing level * Subjects with inflammatory bowel disease
Where it's running
-
National Taiwan University Hospital, Hsinchu Branch
Hsinchu, Taiwan Recruiting -
National Taiwan University Cancer Center
Taipei, Taiwan Recruiting -
National Taiwan University Hospital
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Hsuan-Ho Lin, MD
- Email: tostart21@gmail.com
- Phone: 886-9-72-654-359
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.