Comparing spaced and massed alcohol avoidance training for alcohol use disorder
The Effectiveness of Spaced Versus Massed Alcohol Avoidance Training in Inpatient Alcohol Use Disorder Treatment: A Multisite Randomized Trial
This study is testing whether spreading out alcohol avoidance training over four weeks works better than cramming it into one week for people with alcohol use disorder.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 234 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IrisZorg Academic / other |
| Locations | 1 site (Arnhem, Gelderland) |
| Trial ID | NCT05631366 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the effectiveness of spaced versus massed Alcohol Avoidance Training (AAT) sessions for individuals with alcohol use disorder (AUD). Participants will be randomly assigned to either the spaced group, where AAT sessions are spread over four weeks, or the massed group, where sessions occur within one week following detoxification. Both groups will receive AAT in addition to routine clinical care in an inpatient setting. The study will assess changes in alcohol consumption and avoidance tendencies as a result of the different training schedules.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with a primary diagnosis of alcohol use disorder who are proficient in Dutch.
Not a fit: Patients with severe current psychiatric symptoms that may jeopardize their safety or study adherence will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance treatment strategies for alcohol use disorder by identifying the most effective training schedule for reducing alcohol consumption.
How similar studies have performed: While spaced learning has shown promise in other fields, this specific approach to Alcohol Avoidance Training has not been extensively tested, making it a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * A primary diagnosis of alcohol use disorder (meeting the DSM-5 criteria (American Psychiatric Association, 2013); * Age of at least 18 years or older; * Good Dutch language proficiency; * Written informed consent. Exclusion Criteria: Severe, current psychiatric symptoms (especially manic, psychotic, suicidal and aggressive symptoms) that may endanger participants or others and jeopardize study adherence (determined on a case-by-case basis. The staff member who will provide the AAT information, informed consent and instruction will always consult one of the principal investigators in that case).
Where this trial is running
Arnhem, Gelderland
- IrisZorg — Arnhem, Gelderland, Netherlands (Recruiting)
Study contacts
- Study coordinator: Tom Kalisvaart
- Email: t.kalisvaart@iriszorg.nl
- Phone: +31 (0)88 606 1153
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.