Comparing skin temperature responses to heat stress with and without cooling methods
Skin Surface and Intradermal Temperature Responses to Heat Stress
This study is testing how healthy adults' skin temperatures react to heat stress with and without different cooling methods to see which works better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | University of Texas Southwestern Medical Center Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT06593067 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate how skin surface and intradermal temperatures respond to heat stress in healthy adults, both with and without the application of cooling techniques such as evaporative and convective cooling. Participants will be exposed to controlled heat conditions, and their thermoregulatory responses will be measured to understand the differences in temperature regulation. The study will help clarify the relationship between surface and intradermal temperatures during heat exposure and the effectiveness of cooling methods. By assessing these responses, the research seeks to enhance our understanding of human thermoregulation under heat stress.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults without significant underlying medical conditions.
Not a fit: Patients with chronic medical conditions, heart disease, or those taking medications that affect thermoregulation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve strategies for managing heat stress and enhance safety measures for individuals exposed to high temperatures.
How similar studies have performed: While there have been studies on thermoregulation, this specific comparison of surface and intradermal temperature responses with cooling methods is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Free of any significant underlying medical problems based upon a detailed medical history and physical exam. * Normal resting electrocardiogram. Exclusion Criteria: * Known heart disease; other chronic medical conditions requiring regular medical therapy including cancer, diabetes, neurological diseases, and uncontrolled hypertension, etc.; as well as serious abnormalities detected on routine screening. * Individuals who are pregnant, planning to become pregnant, or breastfeeding. * Taking prescribed medications (such as beta blockers and non-dihydropyridine calcium channel blockers) or over-the-counter medications that have known influences on thermoregulatory response. * Current smokers, as well as individuals who regularly smoked within the past 3 years.
Where this trial is running
Dallas, Texas
- Institute for Exercise and Environmental Medicine — Dallas, Texas, United States (Recruiting)
Study contacts
- Principal investigator: Craig Crandall, Ph.D. — UT Southwestern Medical Center
- Study coordinator: Taysom Wallace, MS
- Email: taysomwallace@texashealth.org
- Phone: 214-345-5022
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.